17881-56-0Relevant articles and documents
Prediction of perception: Probing the hOR17-4 olfactory receptor model with silicon analogues of bourgeonal and lilial
Doszczak, Leszek,Kraft, Philip,Weber, Hans-Peter,Bertermann, Ruediger,Triller, Annika,Hatt, Hanns,Tacke, Reinhold
, p. 3367 - 3371 (2007)
(Figure Presented) Sense and sensibility: Silicon analogues of the lily-of-the-valley odorants lilial and bourgeonal demonstrate that the electronic surface structure determines the interaction of an odorant with its olfactory receptor. The subtle changes
Hydrocarbon-Soluble Bis(trimethylsilylmethyl)calcium and Calcium-Iodine Exchange Reactions at sp2-Hybrized Carbon Atoms
Koch, Alexander,Wirgenings, Marino,Krieck, Sven,G?rls, Helmar,Pohnert, Georg,Westerhausen, Matthias
, p. 3981 - 3986 (2017/10/31)
Hydrocarbon-soluble and highly reactive [(L)xCa(CH2SiMe3)2] (L = tetrahydropyran, x = 4 (2a); L = tmeda, x = 2 (2b)) is synthesized by the metathesis reaction of Me3SiCH2CaI (1-I) with KCH2SiMe3. The durability of 2a in tetrahydropyran solution at 0 °C is sufficiently high for subsequent chemical transformations. The reaction of ICH2SiMe3 with calcium in diethyl ether yields unique cage compound [(Et2O)2Ca(I)2·(Et2O)2Ca(I)(OEt)·(Et2O)Ca(I)(CH2SiMe3)] (3). We demonstrate that alkylcalcium complexes are valuable reagents for calcium-iodine exchange reactions at Csp2-I functionalities.
Further studies on the iodination of aryltrimethylsilanes
Jacob,Chen,Stec
, p. 611 - 614 (2007/10/02)
Aryltrimethylsilanes can be readily iodinated using iodine monochloride and a silver salt in methanol. This procedure works well with aromatic rings that contain a deactivating group and is compatible with sensitive functional groups. To illustrate this a carbobenzyloxy protected 4-trimethylsilylphenylalanine ester was iodinated in good yield. The use of iodine monochloride instead of iodine results in faster reaction times than previously reported and reduced the waste of iodine, which would be beneficial in procedures where the use of other isotopes of iodine would be desired. Careful choice of solvents also allows the monoiodination of 1,4-bis(trimethylsilyl)benzene in good yield, which could prove useful in the synthesis of novel arylsilanes.