17972-14-4

Basic information

• Product Name: Methanamine, N-[(3,4-dimethoxyphenyl)methylene]-
• CAS NO: 17972-14-4
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.219
• Mol File: 17972-14-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Methanamine, N-[(3,4-dimethoxyphenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanamine, N-[(3,4-dimethoxyphenyl)methylene]-(17972-14-4)
• EPA Substance Registry System: Methanamine, N-[(3,4-dimethoxyphenyl)methylene]-(17972-14-4)

Safety Data

• Hazardous Substances Data: 17972-14-4(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 
• 63-64-9 N-methylveratrylamine 

Downstream Products

• 91613-80-8 trans-3-(3,4-dimethoxyphenyl)-4-hydroxy-2-methyl-3,4-dihydro-1(2H)-isoquinolone 
• 91613-80-8 cis-3-(3,4-dimethoxyphenyl)-4-hydroxy-2-methyl-3,4-dihydro-1(2H)-isoquinolone 
• 91613-77-3 trans-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-4-hydroxy-2-methyl-3,4-dihydro-1(2H)-isoquinolone 
• 91613-77-3 cis-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-4-hydroxy-2-methyl-3,4-dihydro-1(2H)-isoquinolone 
• 122547-39-1 3-<(3,4-dimethoxyphenyl)methylene>-6-methoxyisobenzofuran-1(3H)-one 
• 122547-31-3 (E) 3-(3,4-dimethoxyphenylmethylene)-6-methoxy-2-methyl-2,3-dihydro-1H-isoindol-1-one 
• 109329-00-2 3-(3,4-dimethoxyphenyl)methyl-3-hydroxy-6-methoxy-2-methyl-2,3-dihydro-1H-isoindol-1-one 
• 109329-08-0 N-<3,4-dimethoxyphenyl(5-methoxy-3-oxo-1,3-dihydroisobenzofuran-1-yl)methyl>-N-methylacetamide 
• 109329-08-0 N-<3,4-dimethoxyphenyl(5-methoxy-3-oxo-1,3-dihydroisobenzofuran-1-yl)methyl>-N-methylacetamide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 110773-42-7 3-(3,4-Dimethoxy-phenyl)-2-methyl-3,4-dihydro-2H-isoquinolin-1-one 
• 362057-67-8 N-[(3,4-dimethoxyphenyl)(diphenylphosphinoyl)methyl]-N-methylamine 
• 850764-58-8 C₂₀H₁₇NO₅ 
• 63-64-9 N-methylveratrylamine 

Relevant articles and documents

Mechanosynthesis of N-methyl imines using recyclable imidazole-based acid-scavenger: In situ formed ionic liquid as catalyst and dehydrating agent

1,1′-(1,4-Butanediyl)bis(imidazole) was prepared by a modified method and its application as an efficient promoter was demonstrated for the mechanosynthesis of N-methyl imines using ball milling as a non-conventional process under solvent-free conditions. In this new protocol design, the bis-imidazole acted as a recyclable acid-scavenging agent. This efficient approach to the N-methyl imines displays a combination of the synthetic virtues of a non-conventional condensation reaction with ecological benefits and convenience of a facile mechanosynthetic process. The current method has advantages such as reduced waste by avoiding solvent, exclusion of hazardous materials during the reaction, elimination of handling an anhydrous gas in an evacuated container or a solution of methylamine in ethanol, good yields for relatively unreactive benzaldehydes containing electron-donating substituents, short reaction times, and metal- and acid-free conditions. Furthermore, the promoter was easily regenerated and reused several times with no significant loss of activity.

A telescopic one-pot synthesis of β-lactam rings using amines as a convenient source of imines

A facile synthetic approach to substituted β-lactams was designed, using secondary benzylic amines and acid chlorides as starting materials. The reactions proceeded smoothly and all the products were obtained in good yields.

A novel construction of 2-benzazepine scaffold based on TiCl 4-mediated tandem Mannich reaction - Aromatic electrophilic substitution

A novel construction of 2-benzazepine derivatives based on TiCl 4-mediated tandem Mannich reaction of electron-rich benzyl iminium ions with alkenyl ethers and Friedel - Crafts-type alkylation is described. The protocol is amenable to provide the tricyclic furo[3,2-d][2]benzazepine and pyrano[3,2-d][2]benzazepine derivatives, respectively, with 2,3-dihydrofuran or 3,4-dihydro-2H-pyran as the substrates.