91613-80-8

Basic information

• Product Name: 1(2H)-Isoquinolinone, 3-(3,4-dimethoxyphenyl)-3,4-dihydro-4-hydroxy-2-methyl-, cis-
• CAS NO: 91613-80-8
• Molecular Formula: C18H19NO4
• Molecular Weight: 313.353
• Mol File: 91613-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(2H)-Isoquinolinone, 3-(3,4-dimethoxyphenyl)-3,4-dihydro-4-hydroxy-2-methyl-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Isoquinolinone, 3-(3,4-dimethoxyphenyl)-3,4-dihydro-4-hydroxy-2-methyl-, cis-(91613-80-8)
• EPA Substance Registry System: 1(2H)-Isoquinolinone, 3-(3,4-dimethoxyphenyl)-3,4-dihydro-4-hydroxy-2-methyl-, cis-(91613-80-8)

Safety Data

• Hazardous Substances Data: 91613-80-8(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 87-41-2 2-benzofuran-1(3H)-one 
• 17972-14-4 3,4-dimethoxybenzylidenemethylamine 

Relevant articles and documents

Condensation of cyclic and acyclic imines with phthalide anions. Synthesis of protoberberines and substituted 3,4-dihydro-2-methyl-1(2H)-isoquinolones

3,4-Dihydroisoquinolines react with anions derived from phthalides and 3-methylphthalides in tetrahydrofuran yielding 13-hydroxy-8-oxotetrahydroprotoberberines and 13-hydroxy-13-methyl-8-oxotetrahydroprotoberberines, respectively.Only one of two possible diastereomers is formed.The lactams may be reduced to the corresponding protoberberines with lithium aluminium hydride.The reaction of the acyclic imine, 3,4-dimethoxybenzylidenemethylamine, with anions derived from phthalide, 3-phenylphthalide, and 5,6-dimethoxyphthalide, has been investigated.In all cases separable mixtures of diastereomeric substituted 3,4-dihydro-1(2H)-isoquinolones were formed.