179728-45-1

Basic information

• Product Name: 5-sec-Butyl-2-(2,2-diethoxy-ethoxy)-benzaldehyde
• Synonyms: 5-sec-Butyl-2-(2,2-diethoxy-ethoxy)-benzaldehyde
• CAS NO: 179728-45-1
• Molecular Weight: 294.391
• Mol File: 179728-45-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-sec-Butyl-2-(2,2-diethoxy-ethoxy)-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-sec-Butyl-2-(2,2-diethoxy-ethoxy)-benzaldehyde(179728-45-1)
• EPA Substance Registry System: 5-sec-Butyl-2-(2,2-diethoxy-ethoxy)-benzaldehyde(179728-45-1)

Safety Data

• Hazardous Substances Data: 179728-45-1(Hazardous Substances Data)

Upstream product

• 99-71-8 4-(1-methylpropyl)phenol 
• 59893-28-6 5-(1-methylpropyl)salicylaldehyde 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Relevant articles and documents

3-Benzo[b]furyl- and 3-benzo[b]thienylaminobutyric acids as GABA(B) ligands. Synthesis and structure-activity relationship studies

Baclofen (β-p-chlorophenyl GABA) is one of the selective agonists for the bicuculline-insensitive GABA(B) receptors. In the search for new compounds that bind to GABA(B) receptors it is very important to clarify the structural requirements. We report the syntheses of and binding studies on various 3- heteroaromatic (benzo[b]furan and benzo[b]thiophen)aminobutyric acids. The 4- amino-3-(7-methyl-benzo[b]furan-2-yl)butanoic acid 8g is a potent and specific ligand for GABA(B) receptors, with an IC50 value of 5.4 μM in the displacement of [3H]GABA.