59893-28-6

Basic information

• Product Name: Benzaldehyde, 2-hydroxy-5-(1-methylpropyl)-
• Synonyms: 5-(butan-2-yl)-2-hydroxybenzaldehyde;5-(SEC-BUTYL)-2-HYDROXYBENZENECARBALDEHYDE
• CAS NO: 59893-28-6
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.23
• Mol File: 59893-28-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzaldehyde, 2-hydroxy-5-(1-methylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-hydroxy-5-(1-methylpropyl)-(59893-28-6)
• EPA Substance Registry System: Benzaldehyde, 2-hydroxy-5-(1-methylpropyl)-(59893-28-6)

Safety Data

• Hazardous Substances Data: 59893-28-6(Hazardous Substances Data)

Upstream product

• 99-71-8 4-(1-methylpropyl)phenol 
• 67-66-3 chloroform 
• 50-00-0 formaldehyd 

Downstream Products

• 179728-45-1 5-sec-Butyl-2-(2,2-diethoxy-ethoxy)-benzaldehyde 
• 59746-97-3 (5-sec-butyl-2-hydroxyphenyl)(phenyl)methanone 

Relevant articles and documents

COMPOUNDS USEFUL FOR THE TREATMENT OF METABOLIC DISORDERS AND SYNTHESIS OF THE SAME

The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

3-Benzo[b]furyl- and 3-benzo[b]thienylaminobutyric acids as GABA(B) ligands. Synthesis and structure-activity relationship studies

Baclofen (β-p-chlorophenyl GABA) is one of the selective agonists for the bicuculline-insensitive GABA(B) receptors. In the search for new compounds that bind to GABA(B) receptors it is very important to clarify the structural requirements. We report the syntheses of and binding studies on various 3- heteroaromatic (benzo[b]furan and benzo[b]thiophen)aminobutyric acids. The 4- amino-3-(7-methyl-benzo[b]furan-2-yl)butanoic acid 8g is a potent and specific ligand for GABA(B) receptors, with an IC50 value of 5.4 μM in the displacement of [3H]GABA.