179870-09-8

Basic information

• Product Name: (E)-3-[5-(4-Nitro-phenyl)-furan-2-yl]-acryloyl azide
• Synonyms: (E)-3-[5-(4-Nitro-phenyl)-furan-2-yl]-acryloyl azide
• CAS NO: 179870-09-8
• Molecular Weight: 284.231
• Mol File: 179870-09-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-[5-(4-Nitro-phenyl)-furan-2-yl]-acryloyl azide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-[5-(4-Nitro-phenyl)-furan-2-yl]-acryloyl azide(179870-09-8)
• EPA Substance Registry System: (E)-3-[5-(4-Nitro-phenyl)-furan-2-yl]-acryloyl azide(179870-09-8)

Safety Data

• Hazardous Substances Data: 179870-09-8(Hazardous Substances Data)

Upstream product

• 7147-77-5 5-(4-nitrophenyl)-2-furaldehyde 
• 62806-39-7 3-<5-(4-Nitrophenyl)-2-furyl>propenoic acid 

Relevant articles and documents

Synthesis of 2-arylfuro[3,2-c]pyridines and their derivatives

A series of 2-arylfuro[3,2-c]pyridines was synthesized. 3-(5-Aryl-2-furyl)propenoic acids 1a-1h were converted to the acid azides 2a-2h, which in turn were cyclized to give 2-arylfuro[3,2-c]pyridine-4(5H)-ones 4a-4h by heating in Dowtherm. The pyridones 4a-4f were aromatized with phosphorus oxychloride to the 2-aryl-4-chlorofuro[3,2-c]pyridines 5a-5f, which were reduced with zinc and acetic acid to the title compounds 6a-6f. Reacted with phosphorus(V) sulfide, the pyridones 4a-4f yielded the corresponding thiones 7a-7f.