180295-80-1

Basic information

• Product Name: (E)-4-Benzyloxycarbonylamino-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester
• CAS NO: 180295-80-1
• Molecular Weight: 332.4
• Mol File: 180295-80-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-Benzyloxycarbonylamino-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-Benzyloxycarbonylamino-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester(180295-80-1)
• EPA Substance Registry System: (E)-4-Benzyloxycarbonylamino-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester(180295-80-1)

Safety Data

• Hazardous Substances Data: 180295-80-1(Hazardous Substances Data)

Upstream product

• 22586-32-9 N-Benzyloxycarbonylglycine imidazolide 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 123-75-1 pyrrolidine 
• 67706-69-8 ethyl 4-Benzyloxycarbonylamino-3-oxobutanoate 

Downstream Products

• 159770-35-1 C₁₇H₁₈N₂O₇ 
• 159770-30-6 5-benzyloxycarbonylaminomethyl-3-methylisoxazole-4-carboxylic acid 
• 159770-29-3 ethyl 5-benzyloxycarbonylaminomethyl-3-methylisoxazole-4-carboxylate 

Relevant articles and documents

1,3-Dipolar cycloaddition route to nitrogen heterocyclic triones

1,3-Dipolar cycloaddition of nitrile oxides, formed in situ by dehydration of primary nitro compounds, with pyrrolidine enamines of protected γ- or δ-amino-β-keto esters affords isoxazole-4-carboxylates; these undergo lactam formation and N-O bond cleavage to afford 3-acyltetramic acids and 3-acyl-4-hydroxypyridin-2-ones.