18069-68-6

Basic information

• Product Name: 5B-Androstan-3-one
• Synonyms: 5B-Androstan-3-one
• CAS NO: 18069-68-6
• Molecular Formula: C19H30 O
• Molecular Weight: 0
• Mol File: 18069-68-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5B-Androstan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5B-Androstan-3-one(18069-68-6)
• EPA Substance Registry System: 5B-Androstan-3-one(18069-68-6)

Safety Data

• Hazardous Substances Data: 18069-68-6(Hazardous Substances Data)

Upstream product

• 2872-90-4 Δ⁴-Androsten-3-on 
• 1224-92-6 5beta-Androstan-3alpha-ol 
• 52225-35-1 5β-androst-16-en-3-one 
• 2872-90-4 4-androsten-3-one 
• 64-17-5 ethanol 
• 53-42-9 Etiocholanolone 
• 36025-82-8 3-oxoandrost-4-en-17α-yl benzoate 
• 396079-66-6 17α-benzoyloxy-5β-androstanone-(3) 

Relevant articles and documents

Stereochemistry of the Palladium-catalyzed Hydrogenation of 3-Oxo-4-ene Steroids. V. A Kinetic Study in Basic and Acidic Media

Effects of the β-methyl group at C-10 and some oxygen functions (=O, OH, OAc) at C-11, C-17, and C-20 on the rates of hydrogenation of 3-oxo-4-ene steroids have been studied with palladium catalyst in pyridine or THF/HBr as solvent.In contrast to the hydrogenation in pyridine, the rate in THF/HBr was greatly depressed by the presence of 10β-methyl group.The reactivity of the steroids was enhanced by the oxygen functions, in particular, by 11, 17-dioxo group.The effects of the substituents are discussed from a mechanistic consideration based on the obtained results.

Oxidation process

A novel liquid phase oxidation process using silver silicate as the oxidizing agent which is particularly adapted for oxidation of a hydroxy attached to a carbon atom to a carbonyl group.