36025-82-8Relevant articles and documents
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Loibner,H.,Zbiral,E.
, p. 417 - 425 (1977)
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Structure-based design and synthesis of novel potent Na+,K +-ATPase inhibitors derived from a 5α,14α-androstane scaffold as positive inotropic compounds
De Munari, Sergio,Cerri, Alberto,Gobbini, Mauro,Almirante, Nicoletta,Banfi, Leonardo,Carzana, Giulio,Ferrari, Patrizia,Marazzi, Giuseppe,Micheletti, Rosella,Schiavone, Antonio,Sputore, Simona,Torri, Marco,Zappavigna, Maria Pia,Melloni, Piero
, p. 3644 - 3654 (2007/10/03)
The design, synthesis, and biological properties of novel inhibitors of the Na+,K+-ATPase as potential positive inotropic compounds are reported. Following our model of superposition between cassaine and digitoxigenin, digitalis-like
Efficacious modification of the Mitsunobu reaction for inversions of sterically hindered secondary alcohols
Martin,Dodge
, p. 3017 - 3020 (2007/10/02)
A practical modification of the Mitsunobu protocol for effecting stereochemical inversions of alcohols has been discovered in which use of p-nitrobenzoic acid as the nucleophilic partner results in significantly improved yields with relatively hindered su