1807-02-9 Usage
Description
11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one, also known as (11α,17β)-11,17-dihydroxy-17-methylandrost-4-en-3-one, is a testosterone derivative and an adrenal steroid hormone with glucocorticoid activity. It is characterized by its ability to cause increased zinc uptake in human cell cultures, which can have various implications in cellular functions and health.
Uses
Used in Pharmaceutical Industry:
11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one is used as a pharmaceutical agent for its glucocorticoid activity. The expression is: 11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one is used as a glucocorticoid hormone for its role in modulating the immune system and anti-inflammatory effects.
Used in Research Applications:
In the field of research, 11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one is used as a research tool for studying the effects of glucocorticoids on cellular processes and the role of zinc uptake in various biological functions. The expression is: 11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one is used as a research compound for investigating the mechanisms of glucocorticoid action and zinc homeostasis in cells.
Used in Endocrinology:
11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one is also used in endocrinology to understand the role of adrenal steroid hormones in the regulation of various physiological processes. The expression is: 11alpha,17beta-dihydroxy-17-methylandrost-4-en-3-one is used as an endocrine hormone for studying the effects of adrenal steroid hormones on the body's metabolic and immune responses.
Check Digit Verification of cas no
The CAS Registry Mumber 1807-02-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,0 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1807-02:
(6*1)+(5*8)+(4*0)+(3*7)+(2*0)+(1*2)=69
69 % 10 = 9
So 1807-02-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O3/c1-18-8-6-13(21)10-12(18)4-5-14-15-7-9-20(3,23)19(15,2)11-16(22)17(14)18/h10,14-17,22-23H,4-9,11H2,1-3H3
1807-02-9Relevant articles and documents
Application of α- and β-naphthoflavones as monooxygenase inhibitors of Absidia coerulea KCh 93, Syncephalastrum racemosum KCh 105 and Chaetomium sp. KCh 6651 in transformation of 17α-methyltestosterone
Janeczko, Tomasz,Pop?oński, Jaros?aw,Koz?owska, Ewa,Dymarska, Monika,Huszcza, Ewa,Kostrzewa-Sus?ow, Edyta
, p. 178 - 184 (2018/03/26)
In this work, 17α-methyltestosterone was effectively hydroxylated by Absidia coerulea KCh 93, Syncephalastrum racemosum KCh 105 and Chaetomium sp. KCh 6651. A. coerulea KCh 93 afforded 6β-, 12β-, 7α-, 11α-, 15α-hydroxy derivatives with 44%, 29%, 6%, 5% and 9% yields, respectively. S. racemosum KCh 105 afforded 7α-, 15α- and 11α-hydroxy derivatives with yields of 45%, 19% and 17%, respectively. Chaetomium sp. KCh 6651 afforded 15α-, 11α-, 7α-, 6β-, 9α-, 14α-hydroxy and 6β,14α-dihydroxy derivatives with yields of 31%, 20%, 16%, 7%, 5%, 7% and 4%, respectively. 14α-Hydroxy and 6β,14α-dihydroxy derivatives were determined as new compounds. Effect of various sources of nitrogen and carbon in the media on biotransformations were tested, however did not affect the degree of substrate conversion or the composition of the products formed. The addition of α- or β-naphthoflavones inhibited 17α-methyltestosterone hydroxylation but did not change the percentage composition of the resulting products.
