5419-48-7

Basic information

• Product Name: (8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
• Synonyms: (8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione;17beta-Hydroxy-17-methylandrost-4-ene-3,11-dione
• CAS NO: 5419-48-7
• Molecular Formula: C₂₀H₂₈O₃
• Molecular Weight: 316.43452
• Mol File: 5419-48-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 475.7°Cat760mmHg
• Flash Point: 255.6°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 4.78E-11mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: (8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione(5419-48-7)
• EPA Substance Registry System: (8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione(5419-48-7)

Safety Data

• Hazardous Substances Data: 5419-48-7(Hazardous Substances Data)

Usage

Description

(8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione is a steroid compound derived from testosterone, featuring a cyclopenta[a]phenanthrene backbone with a hydroxyl group at the 17th position and ketone groups at positions 3 and 11. This molecule is known for its potent androgenic and anabolic effects, playing a crucial role in controlling male characteristics, reproductive system development, and regulating muscle mass, bone density, and red blood cell production.

Uses

Used in Pharmaceutical Industry:
(8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione is used as a pharmaceutical agent for its strong androgenic and anabolic effects, aimed at treating conditions related to muscle wasting, osteoporosis, and anemia due to its influence on muscle mass, bone density, and red blood cell production.
Used in Sports Performance Enhancement:
In the field of sports, (8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione is used as a performance-enhancing substance to increase muscle mass and strength, although its use is often controversial and may be banned in competitive sports due to its potent effects.
Used in Research and Development:
This steroid compound is also utilized in research and development for understanding the mechanisms of androgen and anabolic actions, as well as for the development of new drugs targeting muscle and bone health, and potentially for the treatment of conditions like androgen deficiency or related disorders.

InChI:InChI=1/C20H28O3/c1-18-8-6-13(21)10-12(18)4-5-14-15-7-9-20(3,23)19(15,2)11-16(22)17(14)18/h10,14-15,17,23H,4-9,11H2,1-3H3/t14-,15-,17+,18-,19-,20-/m0/s1

Upstream product

• 1807-02-9 11α,17β-Dihydroxy-17α-methylandrost-4-en-3-one 
• 58-18-4 17-methyltestosterone 

Downstream Products

• 1043-10-3 11β-hydroxy-17α-methyltestosterone 

Relevant articles and documents

Preparation of [1,2-3H]17-alpha-methyltestosterone and of some unlabelled derivatives.

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