181059-80-3

Basic information

• Product Name: Benzenamine, 2-(1,1-diethoxy-2,2,3,3,4,4,4-heptafluorobutyl)-
• CAS NO: 181059-80-3
• Molecular Formula: C14H16F7NO2
• Molecular Weight: 363.275
• Mol File: 181059-80-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-(1,1-diethoxy-2,2,3,3,4,4,4-heptafluorobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(1,1-diethoxy-2,2,3,3,4,4,4-heptafluorobutyl)-(181059-80-3)
• EPA Substance Registry System: Benzenamine, 2-(1,1-diethoxy-2,2,3,3,4,4,4-heptafluorobutyl)-(181059-80-3)

Safety Data

• Hazardous Substances Data: 181059-80-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 106877-28-5 2-(Nonafluorobutyl)aniline 
• 141-52-6 sodium ethanolate 

Downstream Products

• 200274-52-8 1-(2-Aminophenyl)heptafluorobutan-1-one 

Relevant articles and documents

Synthesis of aminophenyl and methoxyphenyl perfluoroalkyl ketones

The title compounds are obtained by direct hydrolysis of the corresponding 2/4-perfluoroalkyl-substituted anilines and anisoles by the system AcOH/HBr/H2O/Al2O3. A two-step preparation of 2/4-perfluoroacylanilines involves the treatment of the 2/4-perfluoroalkylaniline with sodium ethoxide followed by hydrolysis of the resultant diethyl acetal with hydriodic acid.

Base-mediated reactions of ortho- and para-perfluoroalkylanilines

The title chemistry involves regioselectively a benzylic position of the perfluoroalkyl group and provides an easy access to substituted quinolines and methanes.