181220-07-5Relevant articles and documents
Synthesis of 1-acyl-3,4-dihydroquinazoline-2(1H)-thiones by cyclization of N-[2-(isothiocyanatomethyl)phenyl] amides generated in situ from N-[2-(azidomethyl)phenyl] amides
Kobayashi, Kazuhiro,Matsumoto, Naoki
, p. 923 - 930 (2014/08/05)
An efficient method for the preparation of 1-acyl-3,4-dihydroquinazoline- 2(1H)-thiones 5 has been developed. The reaction of N-[2-(azidomethyl)phenyl] amides 3, easily prepared by a three-step sequence starting with (2-aminophenyl)methanols, with Ph