181271-64-7

Basic information

• Product Name: 8-bromo-4-(4-fluoro-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid
• CAS NO: 181271-64-7
• Molecular Weight: 380.237
• Mol File: 181271-64-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-bromo-4-(4-fluoro-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8-bromo-4-(4-fluoro-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid(181271-64-7)
• EPA Substance Registry System: 8-bromo-4-(4-fluoro-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid(181271-64-7)

Safety Data

• Hazardous Substances Data: 181271-64-7(Hazardous Substances Data)

Upstream product

• 462-06-6 fluorobenzene 
• 35504-85-9 (E) 4-(4-fluorophenyl)-4-oxo-2-butenoic acid 
• 23451-95-8 2-amino-5-bromobenzenethiol 

Relevant articles and documents

Efficient microwave enhanced solvent-free synthesis of potent antifungal agents: Fluorinated benzothiazepine fused β-lactam derivatives

A microwave enhanced, facile cycloaddition has been developed for the synthesis of fluorine containing azeto[2,1-d][1,5]benzothiazepine derivatives (Va-m) on the surface of potassium carbonate (K2CO3). Microwave enhanced solvent-free improved synthesis of required 1,5-benzothiazepines is also developed using montmorillonite clay. The synthesized compounds have been screened 'in vitro' for antifungal activity against Rhizoctonia solani, Fusarium oxysporum and Collectotrichum capsici. Most of the compounds have shown good activity against these pathogens.