18215-71-9

Basic information

• Product Name: Benzenemethanol, a-1-hexynyl-a-methyl-
• CAS NO: 18215-71-9
• Molecular Formula: C14H18O
• Molecular Weight: 202.296
• Mol File: 18215-71-9.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-1-hexynyl-a-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-1-hexynyl-a-methyl-(18215-71-9)
• EPA Substance Registry System: Benzenemethanol, a-1-hexynyl-a-methyl-(18215-71-9)

Safety Data

• Hazardous Substances Data: 18215-71-9(Hazardous Substances Data)

Upstream product

• 6940-78-9 4-chlorobutyl bromide 
• 127-66-2 2-Phenyl-3-butyn-2-ol 
• 32359-01-6 hexenylmagnesium bromide 
• 98-86-2 acetophenone 
• 693-02-7 hex-1-yne 
• 66530-04-9 1-hexyn-1-yl-dimethylaluminum 
• 17150-78-6 1-hexyn-1-yl-diisobutylaluminum 
• 676-58-4 methylmagnesium chloride 
• 218793-76-1 triethoxy(hex-1-yn-1-yl)silane 
• 1119-67-1 1-iodo-1-hexyne 
• 17689-03-1 1-hexynyllithium 

Downstream Products

• 1084888-25-4 3-(2-phenyloct-3-yn-2-yl)-1H-indole 
• 1262895-77-1 1,2-dimethyl-3-(2-phenyloct-3-yn-2-yl)-1H-indole 
• 1251926-44-9 methyl 3-(2-phenyloct-3-yn-2-yl)-1H-indole-5-carboxylate 
• 1592890-20-4 (E)-(4-methyldeca-1,5-dien-4-yl)benzene 
• 821017-71-4 2-phenyl-3-octene-2-ol 
• 1206489-19-1 C₁₄H₂₀O 
• 1592891-03-6 (E)-2-phenyloct-2-en-4-yl acetate: 
• 1592891-87-6 (Z)-2-phenyloct-2-en-4-yl acetate: 
• 1309861-32-2 (S)-2-phenyloct-3-yn-2-ol 
• 1190882-61-1 2-phenylocta-2,3-dien-4-yl diphenyl phosphine oxide 
• 75031-50-4 (1,3-Dimethyl-hepta-1,2-dienyl)-benzene 

Relevant articles and documents

Kinetic Resolution of Tertiary Propargylic Alcohols by Enantioselective Cu?H-Catalyzed Si?O Coupling

A broad range of tertiary propargylic alcohols were kinetically resolved by catalyst-controlled enantioselective silylation. This non-enzymatic kinetic resolution is catalyzed by a Cu?H species and makes use of the commercially available precatalyst MesCu/(R,R)-Ph-BPE and a simple hydrosilane as the resolving reagent. Both alkyl,aryl- as well as dialkyl-substituted propargylic alcohols participate, and especially high selectivity factors are achieved when the alkyne terminus carries a TIPS group, which also enables facile post-functionalization in this position (s up to 207).

Alkynylaluminum Synthesis Catalyzed by a Zwitterionic Neodymium(III) Heterobimetallic Compound

The reaction of H{PhB(OxMe2)2C5H5} (OxMe2 = 4,4-dimethyl-2-oxazoline) with Nd(AlMe4)3 (1) provides Me2Al{(OxMe2)2PhBCp}Nd(AlMe4)2

Direct Substitution of Secondary and Tertiary Alcohols to Generate Sulfones under Catalyst- and Additive-Free Conditions

An environmentally benign protocol that affords propargylic sulfones containing highly congested carbon centers from easily accessible alcohols and sulfinic acids with water as the only byproduct is reported. The reaction proceeded via an in situ dehydrative cross-coupling process by taking advantage of the synergetic actions of multiple hydrogen bonds rather than relying on an external catalyst and/or additives to achieve high product distribution.