18249-98-4 Usage
Description
1H-Benzimidazole,1-(methoxymethyl)-(9CI) is a chemical compound with the molecular formula C9H10N2O. It is a derivative of benzimidazole and contains a methoxymethyl group attached to the nitrogen atom. 1H-Benzimidazole,1-(methoxymethyl)-(9CI) has various potential applications in the field of pharmaceuticals and agrochemicals due to its diverse biological activities.
Uses
Used in Pharmaceutical Industry:
1H-Benzimidazole,1-(methoxymethyl)-(9CI) is used as a building block in the synthesis of complex organic molecules for the development of new drugs. Its potential therapeutic effects include antifungal and antiparasitic properties, making it a valuable candidate for the treatment of various infections and diseases.
Used in Agrochemical Industry:
1H-Benzimidazole,1-(methoxymethyl)-(9CI) is used as a component in the development of agrochemicals, such as pesticides and herbicides, due to its ability to inhibit certain enzymes and receptors. This makes it a valuable tool for controlling pests and promoting crop growth.
Used in Drug Discovery and Development:
1H-Benzimidazole,1-(methoxymethyl)-(9CI) is used as a valuable tool in drug discovery and development. Its diverse biological activities and potential to inhibit certain enzymes and receptors make it a promising candidate for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 18249-98-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,4 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18249-98:
(7*1)+(6*8)+(5*2)+(4*4)+(3*9)+(2*9)+(1*8)=134
134 % 10 = 4
So 18249-98-4 is a valid CAS Registry Number.
18249-98-4Relevant articles and documents
Nano indium oxide-catalyzed domino reaction for the synthesis of N-alkoxylated benzimidazoles
Samanta, Satyajit,Mahato, Sachinta,Chatterjee, Rana,Santra, Sougata,Zyryanov, Grigory V.,Majee, Adinath
supporting information, (2020/07/20)
A convenient method has been developed for the selective synthesis of N-alkoxylated benzimidazole derivatives by the cyclocondensation reaction of simple ortho-phenylenediamine, formaldehyde and alcohols in presence of indium oxide nanoparticles as catalyst. The alcohol acts as reactant as well as solvent in this reaction. No other solvents or additives have been used for this reaction. The catalyst can be reused several times without significant loss of catalytic activity. A probable reaction mechanism has been proposed based on some control experiments.
Novel access to 1-substituted-benzimidazoles via benzotriazole-mediated synthesis
Rivera, Augusto,Maldonado, Mauricio,Ríos-Motta, Jaime,Navarro, Miguel Angel,González-Salas, Diego
experimental part, p. 102 - 104 (2010/03/03)
A one-pot good-yielding synthesis of 1-(alcoxymethyl)-1H-benzimidazoles and 1-((1H-benzimidazol-1-yl)methyl)-1H-benzotriazole from N1,N2-bis((1H-benzotriazol-1-yl)methyl)benzene-1,2 -diamine (3) and alcohols is described. The synthesis of 3 from macrocyclic aminal 6H,13H-5:12,7:14-dimethanedibenzo-[d,i][1,3,6,8]tetraazecine (DMDBTA, 1) and benzotriazole is also described. Both these methods are simple, isolation of the products from the reaction mixtures is easy, and the yields are good.
