183064-07-5Relevant articles and documents
Synthesis and evaluation of oligodeoxynucleotides containing 4'-C-substituted thymidines
Wang, Guangyi,Seifert, Wilfried E.
, p. 6515 - 6518 (2007/10/03)
4'-C-Hydroxymethylthymidine was converted to 4'-C-methoxymethylthymidine and 4'-C-aminomethylthymidine, which were incorporated into oligodeoxynucleotides by phosphoramidite chemistry. The modified oligonucleotides exhibit excellent hybridization and significant improvement in stability to snake venom phosphodiesterase.