184896-92-2

Basic information

• Product Name: Benzoyl chloride, 3-[(methylsulfonyl)amino]-
• Synonyms: 3-Methanesulfonylamino-benzoyl chloride
• CAS NO: 184896-92-2
• Molecular Formula: C8H8ClNO3S
• Molecular Weight: 233.67200
• Mol File: 184896-92-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 360.0±44.0 °C(Predicted)
• Density: 1.494±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoyl chloride, 3-[(methylsulfonyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 3-[(methylsulfonyl)amino]-(184896-92-2)
• EPA Substance Registry System: Benzoyl chloride, 3-[(methylsulfonyl)amino]-(184896-92-2)

Safety Data

• Hazardous Substances Data: 184896-92-2(Hazardous Substances Data)

Upstream product

• 28547-13-9 3-(methanesulfonamido)benzoic acid 
• 582-33-2 3-aminobenzoic acid ethyl ester 
• 93884-11-8 ethyl 3-(methylsulfonamido)benzoate 

Downstream Products

• 1357294-91-7 N-[3-(6,7-dimethoxy-3-n-butyl-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]methanesulfonamide 
• 1357294-66-6 4,5-dimethoxy-N-n-butyl-2-{[3-((methylsulfonyl)amino)phenyl]carboxamido}benzamide 
• 119085-49-3 N-[2-Acetyl-4-(3,4-dimethoxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-methanesulfonamide 
• 119085-48-2 N-[4-(3,4-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-methanesulfonamide 
• 119085-50-6 N-[2-Acetyl-4-(3,4-dihydroxy-phenyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-methanesulfonamide 
• 119085-47-1 N-(3-{[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethylamino]-methyl}-phenyl)-methanesulfonamide 

Relevant articles and documents

Cytotoxic potential of novel 6,7-dimethoxyquinazolines

Herein, we report the synthesis and cytotoxicity of a series of substituted 6,7-dimethoxyquinazoline derivatives. The cytotoxic activity of all synthesized compounds has been evaluated against HCT116p53+/+ and HCT116p53 -/- colon cancer cells and a HEY ovarian cancer cell line naturally resistant to cisplatin. Nine of the tested compounds showed significant cytotoxicity in all cell lines at 10 μM. The most promising derivative (7c) showed IC50values of 0.7 and 1.7 μM in the two colon cancer cell lines.

4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline derivatives. II. Their renal vasodilation activity and structure-activity relationship

A series of 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline derivatives showed potent DA1 agonistic activities. We investigated the structure-activity relationship of the racemic compounds of this series. 4- (3,4-Dihydroxyphenyl)-7-metha