185022-13-3

Basic information

• Product Name: Imidazole-1-carboxylic acid (2R,3R,3aS,9aR)-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-yl ester
• CAS NO: 185022-13-3
• Molecular Weight: 558.666
• Mol File: 185022-13-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Imidazole-1-carboxylic acid (2R,3R,3aS,9aR)-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazole-1-carboxylic acid (2R,3R,3aS,9aR)-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-yl ester(185022-13-3)
• EPA Substance Registry System: Imidazole-1-carboxylic acid (2R,3R,3aS,9aR)-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-yl ester(185022-13-3)

Safety Data

• Hazardous Substances Data: 185022-13-3(Hazardous Substances Data)

Upstream product

• 530-62-1 1,1'-carbonyldiimidazole 
• 175013-46-4 (2R,3R,3aS)-2-{[(tert-butyldiphenylsilyl)oxy]methyl}3-hydroxy-2,3,3a,9a-tetrahydro-6H-furo[2’,3’:4,5]oxazole[3,2a]-pyrimidin-6-one 
• 3736-77-4 2,2'-Anhydrouridine 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 175013-51-1 3'-O-(benzyloxyamino)carbonyl-5'-O-tert-butyldiphenylsilyl-2,2'-anhydrouridine 
• 175013-47-5 3'-O-(t-butyldimethylsilyloxyamino)carbonyl-5'-O-tert-butyldiphenylsilyl-2,2'-anhydrouridine 
• 1054654-90-8 C₃₃H₃₄N₄O₉Si 
• 175013-62-4 5'-O-tert-butyldiphenylsilyl-3'-O-(methoxyamino)carbonyl-2,2'-anhydrouridine 
• 185022-14-4 Phenethyl-carbamic acid (2R,3R,3aS,9aR)-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-yl ester 
• 185022-16-6 C₅₅H₆₁N₃O₁₂Si 
• 176685-71-5 1-[(2R,3R,4S,5R)-3-Benzyloxyamino-5-(tert-butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione 
• 175013-53-3 2'-(benzyloxyamino)-5'-O-(tert-butyldiphenylsilyl)-2'-N,3'-O-carbonyl-2'-deoxyuridine 
• 175013-49-7 5'-O-(tert-butyldiphenylsilyl)-2'-N,3'-O-carbonyl-2'-deoxy-2'-(hydroxylamino)uridine 

Relevant articles and documents

2'-Deoxy-2'-alkoxyaminouridines: Novel 2'-substituted uridines prepared by intramolecular nucleophilic ring opening of 2,2'-O-anhydrouridines

Natural and unnatural modified nucleosides and nucleotides play important roles in biology, medicine, and as biomedical research tools. Reported herein is an application of synthetic methodology developed for the stereo- and regiospecific introduction of structural modifications at the 2'-position of uridine nucleosides. A novel class of modified nucleosides, 2'-alkoxylamino-2'-deoxy uridines, are prepared by intramolecular nucleophilic addition of a 3'-tethered alkoxycarbamate nucleophile to the 2'-position with concomitant opening of a 2,2'-anhydrouridine.