18598-80-6

Basic information

• Product Name: L-Phenylalanine, N-(triphenylmethyl)-, methyl ester
• CAS NO: 18598-80-6
• Molecular Formula: C29H27NO2
• Molecular Weight: 421.539
• Mol File: 18598-80-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-(triphenylmethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-(triphenylmethyl)-, methyl ester(18598-80-6)
• EPA Substance Registry System: L-Phenylalanine, N-(triphenylmethyl)-, methyl ester(18598-80-6)

Safety Data

• Hazardous Substances Data: 18598-80-6(Hazardous Substances Data)

Upstream product

• 93266-75-2 C₃₄H₂₈N₄O₂ 
• 15028-44-1 DL-phenylalanine methyl ester 
• 76-83-5 trityl chloride 
• 47672-25-3 N-trityl-L-phenylalanine 
• 63-91-2 L-phenylalanine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 153451-41-3 {[(S)-1-((S)-1-Benzyl-allylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamic acid benzyl ester 
• 107591-62-8 (2R,3S)-dimethyl <2-hydroxy-4-phenyl-3-(tritylamino)butyl>phosphonate 
• 107591-63-9 (2S,3S)-dimethyl <2-hydroxy-4-phenyl-3-(tritylamino)butyl>phosphonate 
• 144422-98-0 Cbz-Phe-Pheψ-Gly-OH 
• 144422-97-9 Cbz-Phe-Pheψ-Glycinol 
• 144422-96-8 (2S)-1-phenyl-2-aminotrityl-3-hexen-6-ol 
• 144422-94-6 (2S,3RS)-1-phenyl-2-aminotrityl-1-penten-3-ol 
• 214072-06-7 (3R,6S)-3,6-dibenzyl-3,6-dihydro-1H-pyridin-2-one 
• 214072-04-5 (2R,1'S)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide 
• 214072-05-6 (3R,6S)-N-[(2,4-Dimethoxyphenyl)methyl]-3,6-dibenzyl-3,6-dihydro-2-pyridone 
• 214072-02-3 1-[N-(1'S)-(1'-benzyl-prop-2'-enyl)amino]methyl-2,4-dimethoxybenzene 
• 153451-36-6 ((S)-1-Benzyl-allyl)-trityl-amine 
• 126410-30-8 (S)-1-phenylbut-3-en-2-amine 
• 107591-60-6 N-trityl-(S)-phenylalaninal 

Relevant articles and documents

Double chirality transmission in trityl amines: Sensing molecular dynamic stereochemistry by circular dichroism and DFT calculations

Con-figured out: The tert-butyl group can be formally seen as "less" sterically demanding (M) than the methyl group (L). This is the case when a CD-active trityl group at the nitrogen atom is used to report the chirality of the carbon substituent with two

Reaction of N-trityl amino acids with BOP: Efficient synthesis of t-butyl esters as well as N-trityl serine- and threonine-β-lactones

Upon exposure to methoxymethylamine and BOP, the stable hydroxybenzotriazolyl amide of TrPheOH was isolated instead of the expected Weinreb amide. This amide behaves as an active amide similar to the Weinreb amide and could be used, among others, for the

Synthesis of alkene dipeptide isosteres employing the Wittig-Still rearrangement

A new approach to the synthesis of alkene dipeptide isosteres is reported which features the use of the [2,3]-Wittig-Still rearrangement, carried out in hexanes. Employing this rearrangement alkene dipeptide isosteres of 'Gly-Xxx' are accessible starting