187837-96-3

Basic information

• Product Name: 1,3-Dioxane-4,6-dione,5-fluoro-2,2-dimethyl-(9CI)
• Synonyms: 1,3-Dioxane-4,6-dione,5-fluoro-2,2-dimethyl-(9CI)
• CAS NO: 187837-96-3
• Molecular Formula: C6H7FO4
• Molecular Weight: 162.1157832
• Product Categories: HALIDE
• Mol File: 187837-96-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxane-4,6-dione,5-fluoro-2,2-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4,6-dione,5-fluoro-2,2-dimethyl-(9CI)(187837-96-3)
• EPA Substance Registry System: 1,3-Dioxane-4,6-dione,5-fluoro-2,2-dimethyl-(9CI)(187837-96-3)

Safety Data

• Hazardous Substances Data: 187837-96-3(Hazardous Substances Data)

Usage

Structure

Fluoro-substituted derivative of 1,3-Dioxane-4,6-dione

Cyclic diester

A cyclic compound with two ester functional groups

Synonyms

5-Fluoro-2,2-dimethyl-1,3-dioxane-4,6-dione

Applications

Organic synthesis and pharmaceutical research

Potential uses

Development of new drugs and as a building block for complex organic molecules

Research status

Properties and potential uses are still under investigation

Further research

Necessary to fully understand its potential applications

Upstream product

• 15568-87-3 5-(hydroxymethylene)-2,2-dimethyl-1,3-dioxan-4,6-dione 
• 473-87-0 2-fluoromalonic acid 
• 67-64-1 acetone 
• 2033-24-1 cycl-isopropylidene malonate 
• 15568-86-2 5-(ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Relevant articles and documents

FLUOROMALONYL HALFTHIOESTERS

The present invention relates to Fluoromalonyl Halfthioesters (F-MAHTs) of formula (I), wherein R1 represents hydrogen, halogen, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl g

An efficient method for α-monofluorination of carbonyl compounds with molecular fluorine: Use of α-hydroxymethylene substituent as directing and activating groups

Molecular fluorine efficiently reacts with α-hydroxymethylene carbonyl compounds to give α-fluoro-α-formyl compounds in a highly site-specific manner. The fluorinated compounds mostly isolated as their hemiacetals with methanol are readily deformylated just by treatment with weak bases affording α-monofluorinated carbonyl compounds. In this fluorination method, the hydroxymethylene group serves not only as a directing group but also as the activating group of carbonyl compounds for fluorination. By this method, a series of α-fluoro carbonyl compounds including esters was synthesized in high yields.