473-87-0 Usage
Description
Propanedioic acid, fluoro-, also known as fluoromalonic acid, is a chemical compound with the molecular formula C3H2F2O4. It is a fluorinated derivative of propanedioic acid, or malonic acid, which is a dicarboxylic acid. The incorporation of fluorine atoms in its structure endows it with unique properties, distinguishing it from its non-fluorinated counterpart. Propanedioic acid, fluorois of interest in various fields due to its potential applications in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, as well as in materials science and as a building block in organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
Propanedioic acid, fluorois used as a key intermediate in the synthesis of pharmaceuticals for its unique reactivity and properties imparted by fluorination. The presence of fluorine can enhance the lipophilicity, metabolic stability, and bioavailability of the resulting drug molecules, making it a valuable component in the development of new medications.
Used in Agrochemical Development:
In the agrochemical industry, Propanedioic acid, fluorois utilized as a building block for the creation of novel compounds with improved pesticidal properties. The fluorinated malonic acid can contribute to the design of more effective and environmentally friendly agrochemicals by enhancing their target specificity and reducing their environmental impact.
Used in Materials Science:
Propanedioic acid, fluorofinds application in materials science, where its unique properties can be leveraged to develop new materials with specific characteristics. The fluorine substitution can influence the material's thermal stability, mechanical properties, and chemical resistance, making it suitable for various high-performance applications.
Used in Organic Synthesis as a Building Block:
As a versatile building block, Propanedioic acid, fluorois employed in organic synthesis to construct a wide range of organic compounds. Its reactivity and the ability to form diverse chemical bonds make it a valuable component in the synthesis of complex organic molecules for various applications, including specialty chemicals and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 473-87-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 473-87:
(5*4)+(4*7)+(3*3)+(2*8)+(1*7)=80
80 % 10 = 0
So 473-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C3H3FO4/c4-1(2(5)6)3(7)8/h1H,(H,5,6)(H,7,8)
473-87-0Relevant articles and documents
Perfluoro allyl fluorosulfate (FAFS): A versatile building block for new fluoroallylic compounds
Wlassics, Ivan,Tortelli, Vito,Carella, Serena,Monzani, Cristiano,Marchionni, Giuseppe
experimental part, p. 6512 - 6540 (2011/10/13)
In this study we will present and discuss both the synthesis of CF 2=CFCF2OSO2F (perfluoroallyl fluorosulfate, FAFS), focusing in particular on the important role of C3F 6/SO3 ratio, reaction temperature and boron catalyst/SO3 ratio on FAFS' yield and selectivity, as well as a wide variety of ionic and radical reactions possible with FAFS. We focused our attention on reactions of FAFS with aliphatic and aromatic alcohols, acyl halides, halides, H2O2, ketones and radicals whose synthesis and reaction mechanisms will be presented and discussed. Particular attention will be devoted to the novel diallyl-fluoroalkyl peroxide obtained. Factors such as pKa and Lowry and Pearson's Hard/Soft Acid-Base Theory which determine the selectivity between Addition/Elimination vs. Nucleophilic Substitution reaction mechanisms on FAFS will also be presented and discussed.
