188660-16-4

Basic information

• Product Name: 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-3-hydroxy-, phenylmethyl ester, (3S)-
• CAS NO: 188660-16-4
• Molecular Formula: C13H15NO3
• Molecular Weight: 233.267
• Mol File: 188660-16-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-3-hydroxy-, phenylmethyl ester, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-3-hydroxy-, phenylmethyl ester, (3S)-(188660-16-4)
• EPA Substance Registry System: 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-3-hydroxy-, phenylmethyl ester, (3S)-(188660-16-4)

Safety Data

• Hazardous Substances Data: 188660-16-4(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 109-00-2 3-HYDROXYPYRIDINE 
• 108-05-4 vinyl acetate 
• 179748-56-2 (+/-)-N-Carbobenzoxy-3-hydroxy-1,2,3,4-tetrahydropyridine 

Downstream Products

• 188660-19-7 (R)-N-Carbobenzoxy-3-hydroxy-1,2,3,4-tetrahydropyridine 
• 80503-94-2 (R)-4-<(Benzyloxycarbonyl)amino>-3-hydroxybutanoic acid 
• 403499-10-5 2-tert-butoxycarbonylmethyl-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 403499-08-1 [1-benzyl-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-2-yl]-acetic acid tert-butyl ester 
• 403499-09-2 [5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-2-yl]-acetic acid tert-butyl ester 
• 403499-02-5 (2R,5S)-5-Acetoxy-2-tert-butoxycarbonylmethyl-piperidine-1-carboxylic acid benzyl ester 
• 403499-05-8 ((2R,5S)-1-Benzyl-5-methanesulfonyloxy-piperidin-2-yl)-acetic acid tert-butyl ester 
• 403499-06-9 ((2R,5R)-5-Acetoxymethyl-1-benzyl-pyrrolidin-2-yl)-acetic acid tert-butyl ester 
• 403499-03-6 ((2R,5S)-5-Acetoxy-1-benzyl-piperidin-2-yl)-acetic acid tert-butyl ester 
• 403499-04-7 ((2R,5S)-1-Benzyl-5-hydroxy-piperidin-2-yl)-acetic acid tert-butyl ester 
• 403499-07-0 ((2R,5R)-1-Benzyl-5-hydroxymethyl-pyrrolidin-2-yl)-acetic acid tert-butyl ester 
• 330985-33-6 (S)-5-Acetoxy-2-methoxy-piperidine-1-carboxylic acid benzyl ester 
• 179915-15-2 trans-5-Acetoxy-2-allyl-1-carbobenzoxypiperidine 
• 188660-17-5 (R)-3-Acetoxy-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Diastereoselective synthesis of 3,5-trans-(+)-(3R,5R)-3-carbomethoxycarbapenam from 3-hydroxypyridine: Questioning the stereochemical assignment of the natural product

An enantio- and diastereoselective synthesis of the methyl ester of 3,5-trans-(3R,5R)-carbapenam-3-carboxylic acid from 3-hydroxypyridine via (2R,5S)-trans-5-acetoxy-2-allylpiperidine has been achieved by employing the piperidine-pyrrolidine ring-contract

A Facile Synthesis of (R)-4-Amino-3-hydroxybutanoic Acid (GABOB) from 3-Hydroxypyridine

(R)-4-Amino-3-hydroxybutanoic acid (GABOB) has been synthesized facilely from 3-hydroxypyridine via 1-carbobenzoxy-1,2,3,4-tetrahydro-3-hydroxypyridine employing lipase-mediated kinetic resolution.