80503-94-2

Basic information

• Product Name: Butanoic acid, 3-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (3R)-
• CAS NO: 80503-94-2
• Molecular Formula: C12H15NO5
• Molecular Weight: 253.255
• Mol File: 80503-94-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 3-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 3-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (3R)-(80503-94-2)
• EPA Substance Registry System: Butanoic acid, 3-hydroxy-4-[[(phenylmethoxy)carbonyl]amino]-, (3R)-(80503-94-2)

Safety Data

• Hazardous Substances Data: 80503-94-2(Hazardous Substances Data)

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 7013-07-2 (R)-4-Amino-3-hydroxybutanoic acid 
• 121505-94-0 N-benzyloxycarbonyl-glycine-N'-methoxy-N'-methylamide 
• 67561-03-9 N-benzyloxycarbonylglycinal 
• 119960-04-2 methyl 4-[(tert-butoxycarbonyl)amino]-3-oxobutanoate 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 87554-49-2 (R)-(-)-methyl N-t-butyloxycarbonyl-3-hydroxy-4-aminobutanoate 
• 82961-77-1 methyl 4-<(benzyloxycarbonyl)amino>-3-oxobutanoate 
• 188660-17-5 (R)-3-Acetoxy-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 188660-16-4 (S)-N-Carbobenzoxy-3-hydroxy-1,2,3,4-tetrahydropyridine 
• 179748-56-2 (+/-)-N-Carbobenzoxy-3-hydroxy-1,2,3,4-tetrahydropyridine 
• 501-53-1 benzyl chloroformate 
• 100-51-6 benzyl alcohol 
• 180520-94-9 methyl (R)-3-acetoxy-4-[(benzyloxycarbonyl)amino]butanoate 

Downstream Products

• 7013-07-2 (R)-4-Amino-3-hydroxybutanoic acid 

Relevant articles and documents

A Facile Synthesis of (R)-4-Amino-3-hydroxybutanoic Acid (GABOB) from 3-Hydroxypyridine

(R)-4-Amino-3-hydroxybutanoic acid (GABOB) has been synthesized facilely from 3-hydroxypyridine via 1-carbobenzoxy-1,2,3,4-tetrahydro-3-hydroxypyridine employing lipase-mediated kinetic resolution.

Enantioselective enzymatic aminolysis and ammonolysis of dimethyl 3-hydroxyglutarate. Synthesis of (R)-4-amino-3-hydroxybutanoic acid

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Simple Three-Step Synthesis of (R)- and (S)-4-Amino-3-hydroxybutanoic Acid (GABOB) by Stereoselective Aldol Addition

A simple synthesis of both (R)- and (S)-GABOB (5) is reported.In the key step, doubly deprotonated (R)- or (S)-2-Hydroxy-1,2,2-triphenylethyl acetate (HYTRA) (1) is added to Cbz-protected glycinal (2).