1900-85-2

Basic information

• Product Name: phenyl 4-methylbenzoate
• Synonyms: benzoic acid, 4-methyl-, phenyl ester; Phenyl 4-methylbenzoate; p-Toluic acid, phenyl ester
• CAS NO: 1900-85-2
• Molecular Formula: C₁₄H₁₂O₂
• Molecular Weight: 212.2439
• Mol File: 1900-85-2.mol
• Article Data: 59

Chemical Properties

• Boiling Point: 342.7°C at 760 mmHg
• Flash Point: 142.4°C
• Density: 1.122g/cm³
• Vapor Pressure: 7.42E-05mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: phenyl 4-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl 4-methylbenzoate(1900-85-2)
• EPA Substance Registry System: phenyl 4-methylbenzoate(1900-85-2)

Safety Data

• Hazardous Substances Data: 1900-85-2(Hazardous Substances Data)

Usage

General Description

Phenyl 4-methylbenzoate is a chemical compound formed by the esterification of phenol and 4-methylbenzoic acid. It is commonly used as a flavoring agent and fragrance ingredient in various consumer products such as perfumes, lotions, and soaps. Phenyl 4-methylbenzoate has a sweet, floral scent that adds a pleasant aroma to these products. Additionally, it is utilized in the manufacturing of pharmaceuticals and in organic synthesis reactions. phenyl 4-methylbenzoate is known for its low toxicity and is considered safe for use in these applications.

Upstream product

• 99-94-5 p-Toluic acid 
• 108-95-2 phenol 
• 13222-85-0 p-methylbenzoic anhydride 
• 139-02-6 sodium phenoxide 
• 153921-22-3 Se-diphenylarsanyl 4-methylbenzenecarboselenoate 
• 17954-26-6 1,2-dihydro-2-phenoxycarbonylisoquinoline-1-carbonitrile 
• 874-60-2 4-methyl-benzoyl chloride 
• 100-66-3 methoxybenzene 
• 106-41-2 4-bromo-phenol 
• 15023-67-3 4-nitrophenyl 4-methylbenzoate 
• 3229-70-7 phenolate 
• 102-09-0 bis(phenyl) carbonate 
• 106-43-4 para-chlorotoluene 
• 71-43-2 benzene 

Downstream Products

• 150175-93-2 4-methyl-N-(thiazol-2-yl)benzamide 
• 6833-18-7 4-methyl-N-phenylbenzamide 
• 33802-08-3 4-methyl-N-(3-nitro-phenyl)-benzamide 
• 92967-43-6 (N-acetyl-sulfanilyl)-p-toluoyl-amine 
• 27410-07-7 3--3-aethinyl-3-hydroxy-propin-(1) 
• 87228-57-7 2-Methylsulfanyl-2-(toluene-4-sulfonyl)-1-p-tolyl-ethanone 
• 35092-35-4 4-Bromomethyl benzoic acid phenyl ester 
• 134-92-9 4-hydroxy-4'-methylbenzophenone 
• 19434-30-1 2-hydroxy-4'-methylbenzophenone 
• 3229-70-7 phenolate 
• 5118-31-0 4-methylbenzoate 
• 41997-73-3 2-Benzenesulfonyl-2-methoxy-1-p-tolyl-ethanone 
• 41997-82-4 2-Methoxy-2-(toluene-4-sulfonyl)-1-p-tolyl-ethanone 
• 937-21-3 4-methylperbenzoic acid 

Relevant articles and documents

Mechanically induced solvent-free esterification method at room temperature

Herein, we describe two novel strategies for the synthesis of esters, as achieved under high-speed ball-milling (HSBM) conditions at room temperature. In the presence of I2 and KH2PO2, the reactions afford the desired esterification derivatives in 45% to 91% yields within 20 min of grinding. Meanwhile, using KI and P(OEt)3, esterification products can be obtained in 24% to 85% yields after 60 min of grinding. In addition, the I2/KH2PO2 protocol was successfully extended to the late-stage diversification of natural products showing the robustness of this useful approach. Further application of this method in the synthesis of inositol nicotinate was also discussed. This journal is

Transition-Metal-Free DMAP-Mediated Aromatic Esterification of Amides with Organoboronic Acids

A new, transition-metal-free, effective method for aromatic esterification of amides with organoboronic acids has been developed. A wide range of benzoate derivatives were obtained with yields ranging from moderate to good. The catalytic reaction shows a broad substrate scope and excellent functional group tolerance. Conceptually, DMAP mediates the reaction and is crucial for this transformation.

Method for preparing diaryl ester compound through efficient catalysis of pyridine palladium

The invention discloses a method for preparing a diaryl ester compound through efficient catalysis of pyridine palladium. The method is used for high-efficiency high-yield preparation of the diaryl ester compound under mild conditions by taking a phenol compound, an iodobenzene compound and carbon monoxide as raw materials, triethylamine as alkali and pyridine palladium as a catalyst. The method provided by the invention has the advantages of less usage amount of the palladium catalyst, high catalytic activity of the palladium catalyst, stability of the palladium catalyst to air, simple operation, short reaction time and high atom economy, opens up a low-cost, green and efficient way for preparation of diaryl ester compounds, and has broad application prospects.