190189-98-1

Basic information

• Product Name: 2-Boc-amino-4-bromomethylpyridine
• Synonyms: 2-Boc-amino-4-bromomethylpyridine;tert-butyl (4-(bromomethyl)pyridin-2-yl)carbamate;(4-Bromomethyl-pyridin-2-yl)-carbamic acid tert-butyl ester
• CAS NO: 190189-98-1
• Molecular Formula: C₁₁H₁₅BrN₂O₂
• Molecular Weight: 287.15
• Product Categories: pharmacetical
• Mol File: 190189-98-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 330.9°Cat760mmHg
• Flash Point: 153.9°C
• Appearance: /
• Density: 1.427g/cm³
• Vapor Pressure: 0.000162mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 2-Boc-amino-4-bromomethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Boc-amino-4-bromomethylpyridine(190189-98-1)
• EPA Substance Registry System: 2-Boc-amino-4-bromomethylpyridine(190189-98-1)

Safety Data

• Hazardous Substances Data: 190189-98-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H15BrN2O2/c1-11(2,3)16-10(15)14-9-6-8(7-12)4-5-13-9/h4-6H,7H2,1-3H3,(H,13,14,15)

Upstream product

• 304873-62-9 (4-hydroxymethylpyridin-2-yl)carbamic acid tert-butyl ester 
• 305329-03-7 2-[N,N-bis(tert-butoxycarbonyl)amino]isonicotinic acid ethyl ester 
• 506-68-3 bromocyane 
• 7732-18-5 water 
• 90101-20-5 tert-Butyl N-(4-methyl-pyridin-2-yl)carbamate 
• 13362-28-2 2-aminoisonicotinic acid 
• 6937-03-7 methyl 2-aminoisonicotinate 
• 639091-75-1 methyl 2-[(tert-butoxycarbonyl)amino]isonicotinate 

Downstream Products

• 1126422-76-1 5-benzyloxy-1-(2-tert-butoxycarbonylamino-pyridin-4-ylmethyl)-3-(2-methoxy-pyridin-3-yl)-1H-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF

The present invention relates generally to therapeutics targeting the bacterium Porphyromonas gingivalis, including its proteases arginine gingipain A/B (Rgp), and their use for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease. In certain embodiments, the invention provides compounds according to Formula I and Formula III, as described herein, and pharmaceutically acceptable salts thereof.

Design and synthesis of potent, orally active, inhibitors of carboxypeptidase U (TAFIa)

A series of 3-mercapto-propionic acid derivatives that function as reversible inhibitors of carboxypeptidase U have been prepared. We present a successful design strategy using cyclic, low basicity guanidine mimetics resulting in potent, selective and bioavailable inhibitors of carboxypeptidase U (TAFIa).

Fibrinogen receptor antagonists

Fibrinogen receptor antagonists having the structure, for example, of STR1 for example STR2