190506-85-5

Basic information

• Product Name: (2R,3R)-3-phenyl-2,3-epoxybutan-1-ol
• Synonyms: (2R,3R)-3-phenyl-2,3-epoxybutan-1-ol
• CAS NO: 190506-85-5
• Molecular Weight: 164.204
• Mol File: 190506-85-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (2R,3R)-3-phenyl-2,3-epoxybutan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-phenyl-2,3-epoxybutan-1-ol(190506-85-5)
• EPA Substance Registry System: (2R,3R)-3-phenyl-2,3-epoxybutan-1-ol(190506-85-5)

Safety Data

• Hazardous Substances Data: 190506-85-5(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 945-93-7 ethyl (E)-3-phenylbut-2-enoate 
• 54976-38-4 (E)-3-phenylbut-2-en-1-ol 

Relevant articles and documents

Prompt determination of absolute configuration for epoxy alcohols via exciton chirality protocol

A microscale protocol for determination of absolute configurations of 2,3-epoxy alcohols is described. 2,3-Disubstituted (cis and trans), 2,2-disubstituted, 2,2,3-trisubstituted, and 2,3,3-trisubstituted epoxy alcohols rendered prominent ECCD signals upon complexing with a Lewis acidic porphyrin tweezer and consequently provide straightforward assignment of chirality for epoxy alcohols. This method proved to be rapid, simple, sensitive, and reliable for the class of molecules listed above. Copyright

Development and application of versatile bis-hydroxamic acids for catalytic asymmetric oxidation

In this article, we describe the development and preliminary results of our new designed C2-symmetric bis-hydroxamic acid (BHA) ligands and the application of the new ligands for vanadium-catalyzed asymmetric epoxidation of allylic alcohols as well as homoallylic alcohols. From this success we demonstrate the versatile nature of BHA in the molybdenum catalyzed asymmetric oxidation of unfunctionalized olefins and sulfides.

Catalytic asymmetric epoxidation

The present invention relates to the synthesis of chiral epoxides via a catalytic asymmetric oxidation of olefins. Additionally, the methodology provides a method of asymmetrically oxidizing sulfides and phosphines. This asymmetric oxidation employs a catalyst system composed of a metal and a chiral bishydroxamic acid ligand, which, in the presence of a stoichiometric oxidation reagent, serves to asymmetrically oxidize a variety of substrates.