19090-03-0

Basic information

• Product Name: Tetrahydro-2H-thiopyran-3-one
• Synonyms: 5,6-Dihydro-2H-thiopyran-3(4H)-one;Tetrahydro-2H-thiopyran-3-one;dihydro-2H-thiopyran-3(4H)-one(SALTDATA: FREE);Dihydro-2H-thiopyran-3(4H)-one;Tetrahydro-2H-thiopyran-3...;THIAN-3-ONE;Dihydro-2H-thiopyran-3(4H)
• CAS NO: 19090-03-0
• Molecular Formula: C₅H₈OS
• Molecular Weight: 116.18
• Mol File: 19090-03-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 195.2°C at 760 mmHg
• Flash Point: 85.3°C
• Appearance: /
• Density: 1.134g/cm³
• Vapor Pressure: 0.424mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: Tetrahydro-2H-thiopyran-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: Tetrahydro-2H-thiopyran-3-one(19090-03-0)
• EPA Substance Registry System: Tetrahydro-2H-thiopyran-3-one(19090-03-0)

Safety Data

• Hazardous Substances Data: 19090-03-0(Hazardous Substances Data)

Usage

General Description

Tetrahydro-2H-thiopyran-3-one is an organic compound classified as a cyclic thioketone. It is a cyclic compound that consists of a tetrahydrothiopyran moiety carrying an oxo substituent. It is a basic structure found in many naturally occurring compounds, especially in sulfur-containing antibiotics. Being a parent hydride of thiopyran, it also has potential uses in the field of organosulfur chemistry. Its potential applications and roles in various chemical reactions are subject to ongoing scientific research.

InChI:InChI=1/C5H8OS/c6-5-2-1-3-7-4-5/h1-4H2

Upstream product

• 22072-19-1 3-Hydroxytetrahydrothiopyran 
• 58509-73-2 ethyl 3-oxothiane-2-carboxylate 
• 63449-37-6 ethyl 4-<(2-ethoxy-2-oxoethyl)sulfanyl>butanoate 
• 38555-40-7 methyl 4-{[2-(methyloxy)-2-oxoethyl]thio}butanoate 
• 38555-41-8 methyl 3-oxo-2,3,4,5-tetrahydro-6H-thiopyran-2-carboxylate 

Downstream Products

• 22072-19-1 3-Hydroxytetrahydrothiopyran 
• 58230-51-6 dihydro-thiopyran-3-one oxime 
• 29431-37-6 tetrahydrothiopyran-3-one-1,1-dioxide 
• 17517-55-4 10-phenyl-3,4-dihydro-2H-thiopyrano[3,2-b]quinoline 
• 77128-43-9 2-phenylthio-thiacyclohexan-3-one 
• 143884-48-4 10-Benzyl-3,4-dihydro-2H,10H-1-thia-10-aza-anthracen-9-one 
• 117593-45-0 N-phenyl-3-aminothiacyclohexane 
• 132611-11-1 2-Phenyl-7-thia-1,2,4-triaza-spiro[4.5]decan-3-one 
• 162321-41-7 (3-Chloro-4-methoxy-phenyl)-[dihydro-thiopyran-(3Z)-ylidene]-amine 
• 152620-07-0 2-Chlor-tetrahydrothiopyran-3-on 
• 1795-09-1 2-methylthiolane 
• 194931-35-6 [(3S,4S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-oxo-4-((R)-3-oxo-tetrahydro-thiopyran-2-yl)-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 194931-37-8 [(2S,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-((2R,4S)-4-methylsulfanyl-3-oxo-tetrahydro-thiopyran-2-yl)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 94158-05-1 3-hydroxytetrahydro-2H-thiopyran-1,1-dioxide 

Relevant articles and documents

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SUBSTITUTED PYRAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF

The present invention relates to compounds according to Formula (I-1) and pharmaceutically acceptable salts thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.

FUSED TRICYCLIC COMPOUNDS FOR USE AS INHIBITORS OF JANUS KINASES

The invention provides novel compounds of formula (I) having the general formula (I) wherein R1, V, W, X, Y and Z are as described herein. Accordingly, the compounds may be provided in pharmaceutically acceptable compositions and used for the treatment of immunological or hyperproliferative disorders.