19407-55-7

Basic information

• Product Name: 8-Chloro-2-phenylquinazolin-4(3H)-one
• Synonyms: 8-Chloro-2-phenylquinazolin-4(3H)-one
• CAS NO: 19407-55-7
• Molecular Weight: 256.691
• Mol File: 19407-55-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 8-Chloro-2-phenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Chloro-2-phenylquinazolin-4(3H)-one(19407-55-7)
• EPA Substance Registry System: 8-Chloro-2-phenylquinazolin-4(3H)-one(19407-55-7)

Safety Data

• Hazardous Substances Data: 19407-55-7(Hazardous Substances Data)

Upstream product

• 53312-77-9 2-amino-3-chlorobenzonitrile 
• 1885-29-6 anthranilic acid nitrile 
• 62484-39-3 2,8-dichloroquinazolin-4(3H)-one 
• 98-80-6 phenylboronic acid 
• 62484-29-1 2,4,8-trichloroquinazoline 
• 62484-22-4 8-chloro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline 
• 6388-47-2 2-amino-3-chlorobenzoic acid 
• 7477-63-6 7-chloroisatin 
• 1670-14-0 benzamidine monohydrochloride 

Relevant articles and documents

Divergent Synthesis of Quinazolin-4(3H)-ones and Tryptanthrins Enabled by a tert-Butyl Hydroperoxide/K3PO4-Promoted Oxidative Cyclization of Isatins at Room Temperature

A synergetic tert-butyl hydroperoxide/K3PO4-promoted oxidative cyclization has been developed for the facile synthesis of various functionalized quinazolin-4(3H)-ones from commercially available isatins and amidine hydrochlorides at room temperature. The synthetic utility of this strategy was illustrated by the convenient synthesis of tryptanthrin derivatives via a self-dimerization of isatins under the same conditions.

HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS

The invention relates to heterocyclic compounds and their use as antibiotics and/or as antibiotic potentiators. The compounds may act as colistin potentiators and SOS inhibitors.