62484-39-3 Usage
Description
4(1H)-Quinazolinone, 2,8-dichlorois a quinazoline derivative characterized by the presence of two chlorine atoms at the 2nd and 8th positions. It is a heterocyclic compound with potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
4(1H)-Quinazolinone, 2,8-dichlorois used as a key intermediate compound for the synthesis of potent CXCR2 antagonists and dipeptidyl peptidase IV (DPP-IV) inhibitors. These inhibitors play a crucial role in the development of drugs targeting various diseases, including type 2 diabetes, inflammatory disorders, and certain types of cancer.
CXCR2 antagonists, derived from 4(1H)-Quinazolinone, 2,8-dichloro-, are employed for their anti-inflammatory properties, making them potential candidates in the treatment of chronic obstructive pulmonary disease (COPD), asthma, and other inflammatory conditions.
DPP-IV inhibitors, on the other hand, are used to manage type 2 diabetes by regulating glucose levels in the body. They work by slowing down the degradation of incretin hormones, which stimulate insulin secretion and reduce glucose production in the liver.
Check Digit Verification of cas no
The CAS Registry Mumber 62484-39-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,8 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 62484-39:
(7*6)+(6*2)+(5*4)+(4*8)+(3*4)+(2*3)+(1*9)=133
133 % 10 = 3
So 62484-39-3 is a valid CAS Registry Number.
62484-39-3Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS
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, (2016/07/05)
The invention relates to heterocyclic compounds and their use as antibiotics and/or as antibiotic potentiators. The compounds may act as colistin potentiators and SOS inhibitors.
Tetrazolo[A]quinazol-5-ones antiallergy and antiulcer agents
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, (2008/06/13)
A series of tetrazolo[a]quinazol-5-ones, methods for their production and use as antiallergy agents and antiulcer agents.
