194724-02-2

Basic information

• Product Name: L-Phenylalanine, N-acetyl-2-bromo-, methyl ester
• CAS NO: 194724-02-2
• Molecular Formula: C12H14BrNO3
• Molecular Weight: 300.152
• Mol File: 194724-02-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-acetyl-2-bromo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-acetyl-2-bromo-, methyl ester(194724-02-2)
• EPA Substance Registry System: L-Phenylalanine, N-acetyl-2-bromo-, methyl ester(194724-02-2)

Safety Data

• Hazardous Substances Data: 194724-02-2(Hazardous Substances Data)

Upstream product

• 863487-03-0 methyl α-acetamido-β-(2-bromophenyl)-acrylate 
• 35356-70-8 Methyl 2-acetamidoacrylate 
• 583-55-1 1-Bromo-2-iodobenzene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 461706-35-4 4-(2-bromophenyl)methylene-2-methyl-5(4H)-oxazolone 
• 194724-01-1 C₁₂H₁₂BrNO₃ 

Downstream Products

• 110592-39-7 (S)-N-acetyl-2,3-dihydroindoline-2-carboxylic acid methyl ester 

Relevant articles and documents

Cation-triggered switchable asymmetric catalysis with chiral aza-crownphos

An aza-crown ether, modified phosphoramidite ligand, has been designed and synthesized. The ON/OFF reversible switch of catalytic activity for its rhodium catalyst was thoroughly investigated in the asymmetric hydrogenation of dehydroamino acid esters modulated by host-guest interactions. In the OFF state, the catalyst is almost inactive (less than 1% conversion) because of the formation of an intermolecular sandwich complex by two aza-crown ether moities and the cationic rhodium metal center. In using alkali-metal-cations as the trigger, the catalytic activity was turned ON and consequently resulted in full conversions and excellent enantioselectivities (up to 98% ee).

Supramolecular chiral phosphorous ligands based on a [2]pseudorotaxane complex for asymmetric hydrogenation

A new type of supramolecular chiral phosphorus-based ligands was prepared from easily available monodentate ligands through complexation between dibenzylammonium salt and dibenzo[24]crown-8 macrocycle. Rhodium complexes with these supramolecular ligands w

Modular monodentate phosphoramidite ligands for rhodium-catalyzed enantioselective hydrogenation

A new class of monodentate phosphoramidite ligands (DpenPhos) has been developed on the basis of the modular concept for Rh(I)-catalyzed asymmetric hydrogenations of a variety of olefin derivatives, affording the corresponding optically active compounds in excellent yields and enantioselectivities. The ligands have the advantages of facile preparation, tunable structure, and broad scope of substrates in their Rh(I) complex-catalyzed asymmetric hydrogenations. Copyright