194736-82-8

Basic information

• Product Name: L-FDAA-D-N-methylalanine
• Synonyms: L-FDAA-D-N-methylalanine
• CAS NO: 194736-82-8
• Molecular Weight: 355.307
• Mol File: 194736-82-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: L-FDAA-D-N-methylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: L-FDAA-D-N-methylalanine(194736-82-8)
• EPA Substance Registry System: L-FDAA-D-N-methylalanine(194736-82-8)

Safety Data

• Hazardous Substances Data: 194736-82-8(Hazardous Substances Data)

Upstream product

• 600-21-5 N-methylalanine 
• 95713-52-3 N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide 
• 29475-64-7 N-methyl-D-alanine 

Relevant articles and documents

Friomaramide, a Highly Modified Linear Hexapeptide from an Antarctic Sponge, Inhibits Plasmodium falciparum Liver-Stage Development

The cold waters of Antarctica are known to harbor a rich biodiversity. Our continuing interest in the chemical analysis of Antarctic invertebrates has resulted in the isolation of friomaramide (1), a new, highly modified hexapeptide, from the Antarctic sponge Inflatella coelosphaeroides. The structure of friomaramide was determined using spectroscopic methods and its configuration established by Marfey's method. Friomaramide, which bears the unusual permethylation of the amino acid backbone and is the longest polypeptide bearing a tryptenamine C-terminus, blocks >90% of Plasmodium falciparum liver-stage parasite development at 6.1 μM.

Jahanyne, an apoptosis-inducing lipopeptide from the marine cyanobacterium lyngbya sp.

An acetylene-containing lipopeptide, jahanyne, was isolated from the marine cyanobacterium Lyngbya sp. Its gross structure was established by spectroscopic analyses, and the absolute configuration was clarified based on a combination of chiral HPLC analyses, spectroscopic analyses, and derivatization reactions. Jahanyne significantly inhibited the growth of human cancer cells and induced apoptosis in HeLa cells.

Two new cyclic pentapeptides from the marine-derived fungus aspergillus versicolor

Two new cyclic pentapeptides, named versicotides A (1) and B (2), were obtained from a marine-derived fungus strain ZLN-60, identified as Aspergillus versicolor. Their structures were established on the basis of chemical and spectroscopic evidence. Versic