194928-82-0 Usage
Description
(6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is a cephalosporin antibiotic belonging to the beta-lactam class of antibiotics. It features a thiazole ring and a cephem ring in its structure, which contribute to its potent antibacterial activity. (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is effective against a broad spectrum of gram-positive and gram-negative bacteria, making it a valuable asset in the medical field for treating various bacterial infections.
Uses
Used in Pharmaceutical Industry:
(6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is used as an antibiotic for the treatment of various bacterial infections. Its application is based on its ability to inhibit bacterial cell wall synthesis, thereby preventing the growth and proliferation of bacteria.
Used in Clinical Settings:
In the clinical setting, (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is used as a therapeutic agent to combat bacterial infections. Its effectiveness against a wide range of bacteria makes it a crucial component in the arsenal of antibiotics used by healthcare professionals to treat patients with bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 194928-82-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,9,2 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 194928-82:
(8*1)+(7*9)+(6*4)+(5*9)+(4*2)+(3*8)+(2*8)+(1*2)=190
190 % 10 = 0
So 194928-82-0 is a valid CAS Registry Number.
194928-82-0Relevant articles and documents
Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879
Yoshida, Yoshiki,Matsuda, Keiji,Sasaki, Hiroshi,Matsumoto, Yoshimi,Matsumoto, Satoru,Tawara, Shuichi,Takasugi, Hisashi
, p. 2627 - 2631 (2007/10/03)
The synthesis, therapeutic efficacy against H. pylori, and preliminary safety of the novel cephem derivative, FR193879 (8a) are described. Compound 8a having a (4-carbamoylmethylthiazol-2-yl)thio moiety at the 3-position and a phenylacetamido at the 7-position was found to have good safety showing a nontoxic dose of 100mg/kg in dogs in a 4-week repeat dose toxicity study and extremely potent therapeutic efficacy against H. pylori, showing 30 times superior activity compared to AMPC, and did not display cross-resistance with CAM or MNZ.
