1950-85-2 Usage
Description
Sodium methanethiosulphonate, with the CAS number 1950-85-2, is a white solid compound that is useful in organic synthesis. It is known for its reactivity and stability in various chemical processes, making it a valuable component in the synthesis of different organic compounds.
Uses
Used in Organic Synthesis:
Sodium methanethiosulphonate is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions. It is particularly useful in the formation of thiol-containing compounds, which are essential in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, sodium methanethiosulphonate is used as a building block for the synthesis of therapeutic agents. Its unique chemical properties allow for the creation of novel drug candidates with potential applications in treating various diseases and medical conditions.
Used in Chemical Research:
Sodium methanethiosulphonate is also utilized in chemical research as a tool to study the properties and behavior of thiol-containing compounds. It can be employed in the development of new methodologies and techniques for the synthesis and modification of thiols, which are important in various fields of chemistry.
Used in Material Science:
In the field of material science, sodium methanethiosulphonate can be used as a precursor for the development of new materials with unique properties. Its ability to form thiol-containing compounds can contribute to the creation of materials with enhanced stability, reactivity, or other desirable characteristics.
Overall, sodium methanethiosulphonate is a versatile compound with a wide range of applications in various industries, including organic synthesis, pharmaceuticals, chemical research, and material science. Its unique chemical properties and reactivity make it a valuable asset in the development of new compounds and materials with potential applications in various fields.
Purification Methods
Recrystallise the salt from H2O (plates as monohydrate) or MeOH. The potassium salt crystallises from H2O, EtOH or MeOH (thick plates) with m 201-202o [Foss Acta Chem Scand 10 868 1956]. The S-benzylisothiouronium salt has m 141-142o (from EtOH) [Kurzer & Powell J Chem Soc 3733 1952]. [Beilstein 4 IV 31.]
Check Digit Verification of cas no
The CAS Registry Mumber 1950-85-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,5 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1950-85:
(6*1)+(5*9)+(4*5)+(3*0)+(2*8)+(1*5)=92
92 % 10 = 2
So 1950-85-2 is a valid CAS Registry Number.
InChI:InChI=1/CH4O2S2.Na/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1/rCH3NaO2S2/c1-6(3,4)5-2/h1H3
1950-85-2Relevant articles and documents
A trisulfide-linked glycoprotein
Bernardes, Goncalo J. L.,Marston, Justin P.,Batsanov, Andrei S.,Howard, Judith A. K.,Davis, Benjamin G.
, p. 3145 - 3147 (2007)
The first member of a novel class of chemoselective reagents, glycosyl methanedithiosulfonates, has been synthesized, identified and employed in the first examples of chemical, site-selective construction of a trisulfide-modified protein with complete conversion. The Royal Society of Chemistry.
PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS
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Page/Page column 4, (2010/07/08)
The present invention relates to new prostaglandin derivatives having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of glaucoma and ocular hypertension.
Interactions of aromatic mannosyl disulfide derivatives with Concanavalin A: synthesis, thermodynamic and NMR spectroscopy studies
Murthy, Bandaru Narasimha,Sinha, Sharmistha,Surolia, Avadhesha,Jayaraman, Narayanaswamy,Szilagyi, Laszlo,Szabo, Ildiko,Koever, Katalin E.
experimental part, p. 1758 - 1763 (2009/12/24)
α-d-Mannopyranosyl units were attached to an aromatic scaffold through disulfide linkages to obtain mono- to trivalent glycosylated ligands for lectin binding studies. Isothermal titration calorimetric (ITC) measurements indicated that binding affinities of these derivatives to Concanavalin A (Con A) were comparable to or slightly higher than that of methyl α-d-mannopyranoside (Ka values in the range of 104 M-1). The stoichiometries of the lectin-ligand complexes were in agreement with the formal valencies (1-3) of the respective ligands indicating cross-linking in interactions with the di- and trivalent derivatives. Multivalency effects could not, however, be observed with the latter. These ligands were shown to bind to the carbohydrate binding site of Con A using saturation transfer difference (STD) NMR competition experiments.
