215956-55-1 Usage
Description
4-BROMO-(1-OXYL-2,2,5,5-TETRAMETHYL-?3-PYRROLINE-3-METHYL) METHANETHIOSULFONATE, also known as the Bromo-analogue of MTSL, is a highly reactive thiol-specific spin-label. It is characterized by its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study, making it a specific conformational probe of thiol site structure. This brown solid is a promising tool for various applications in different industries.
Uses
Used in Biochemistry Research:
4-BROMO-(1-OXYL-2,2,5,5-TETRAMETHYL-?3-PYRROLINE-3-METHYL) METHANETHIOSFONATE is used as a conformational probe for studying thiol site structure in macromolecules. Its minimal rotational freedom and specific binding to thiol groups make it an ideal tool for investigating the structure and dynamics of proteins and other biomolecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-BROMO-(1-OXYL-2,2,5,5-TETRAMETHYL-?3-PYRROLINE-3-METHYL) METHANETHIOSULFONATE is used as a research compound for the development of new drugs targeting thiol-containing enzymes or proteins. Its ability to bind specifically to thiol groups can help in the design of more effective and selective therapeutic agents.
Used in Material Science:
4-BROMO-(1-OXYL-2,2,5,5-TETRAMETHYL-?3-PYRROLINE-3-METHYL) METHANETHIOSULFONATE is used as a reactive spin-label in the development of new materials with specific properties. Its minimal rotational freedom and distance from the covalent disulfide linkage can be exploited to create materials with tailored characteristics, such as improved stability or enhanced reactivity.
Used in Environmental Science:
In environmental science, 4-BROMO-(1-OXYL-2,2,5,5-TETRAMETHYL-?3-PYRROLINE-3-METHYL) METHANETHIOSULFONATE is used as a tool for the detection and monitoring of thiol-containing pollutants. Its high reactivity and specificity for thiol groups make it a valuable asset in the assessment and remediation of contaminated environments.
Check Digit Verification of cas no
The CAS Registry Mumber 215956-55-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,9,5 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 215956-55:
(8*2)+(7*1)+(6*5)+(5*9)+(4*5)+(3*6)+(2*5)+(1*5)=151
151 % 10 = 1
So 215956-55-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H18BrNO3S2/c1-9(2)7(6-16-17(5,14)15)8(11)10(3,4)12(9)13/h13H,6H2,1-5H3
215956-55-1Relevant articles and documents
3-Substituted 4-bromo-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1- yloxyl radicals as versatile synthons for synthesis of new paramagnetic heterocycles
Kalai, Tamas,Balog, Maria,Jekoe, Jozsef,Hideg, Kalman
, p. 1476 - 1482 (2007/10/03)
β-Bromo-α, β-unsaturated electron withdrawing group containing dihydropyrrole nitroxides 2, 3, 4b, and 5b were used for synthesis of dihydropyrrol-1-yloxyl radicals annulated to thiazepine 7, 13 and thiophene 14a-g rings. The 4-bromo-3-formylsubstituted 2,5-dihydropyrrole 5b was also a synthon for the synthesis of 3,4-disubstituted nitroxides 17a-d, 18a-d, 19a- c, 20a-c.
