195141-02-7

Basic information

• Product Name: C₁₆H₂₀OSi
• Synonyms: C₁₆H₂₀OSi
• CAS NO: 195141-02-7
• Molecular Weight: 256.42
• Mol File: 195141-02-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₀OSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₀OSi(195141-02-7)
• EPA Substance Registry System: C₁₆H₂₀OSi(195141-02-7)

Safety Data

• Hazardous Substances Data: 195141-02-7(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 6793-92-6 p-benzyloxyphenylbromide 
• 13132-25-7 4-(trimethylsilyl)phenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 1259290-76-0 C₁₇H₁₈O₄ 
• 7452-95-1 4-trimethylsilylcyclohexan-1-one 
• 1138530-06-9 trimethyl(4-methylenecyclohexyl)silane 

Relevant articles and documents

Cobalt-Catalyzed Desymmetric Isomerization of Exocyclic Olefins

Chiral cyclic olefins, 1-methylcyclohexenes, are versatile building blocks for the synthesis of pharmaceuticals and natural products. Despite the prevalence of these structural motifs, the development of efficient synthetic methods remains an unmet challenge. Herein we report a novel desymmetric isomerization of exocyclic olefins using a series of newly designed chiral cobalt catalysts, which enables a straightforward construction of chiral 1-methylcyclohexenes with diversified functionalities. The synthetic utility of this methodology is highlighted by a concise and enantioselective synthesis of a natural product, β-bisabolene. The versatility of the reaction products is further demonstrated by multifarious derivatizations.