195881-29-9

Basic information

• Product Name: 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-N²-{[2-(4-nitrophenyl)ethoxy]carbonyl}-O⁶-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)guanosine 3'-2-(4-nitrophenyl)ethyl diisopropylphosphoramidite
• Synonyms: 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-N²-{[2-(4-nitrophenyl)ethoxy]carbonyl}-O⁶-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)guanosine 3'-2-(4-nitrophenyl)ethyl diisopropylphosphoramidite
• CAS NO: 195881-29-9
• Molecular Weight: 1209.17
• Mol File: 195881-29-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-N²-{[2-(4-nitrophenyl)ethoxy]carbonyl}-O⁶-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)guanosine 3'-2-(4-nitrophenyl)ethyl diisopropylphosphoramidite(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-N²-{[2-(4-nitrophenyl)ethoxy]carbonyl}-O⁶-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)guanosine 3'-2-(4-nitrophenyl)ethyl diisopropylphosphoramidite(195881-29-9)
• EPA Substance Registry System: 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-N²-{[2-(4-nitrophenyl)ethoxy]carbonyl}-O⁶-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)guanosine 3'-2-(4-nitrophenyl)ethyl diisopropylphosphoramidite(195881-29-9)

Safety Data

• Hazardous Substances Data: 195881-29-9(Hazardous Substances Data)

Upstream product

• 195881-17-5 2-cyano-1-phenylethyl carbonochloridate 
• 108787-34-4 bis(N,N-diisopropylamino)-2-(4-nitrophenyl)ethoxyphosphane 
• 195881-26-6 5'-O-[(2-cyano-1-phenylethoxy)carbonyl]-N²-{[2-(4-nitrophenyl)ethoxy]carbonyl}-O⁶-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)guanosine 

Relevant articles and documents

The (2-cyano-1-phenyl)ethoxycarbonyl (cpeoc) group-a new protecting group for oligoribonucleotide synthesis

The (2- cyano-1-phenyl)ethoxycarbonyl (cpeoc) group was developed as a new base-labile protecting group for the 5-OH function in solid-phase synthesis of oligoribonucleotide by the phosphoramidite approach using the 4- methoxytetrahydropyran-4-yl (mthp) group for 2'-protection. The syntheses of the monomeric building blocks and the first oligoribonucleotides obtained by this approach are described.