19620-35-0

Basic information

• Product Name: 8-Isopropylidene-1,4-dioxa-spiro[4.5]decane
• Synonyms: 8-Isopropylidene-1,4-dioxa-spiro[4.5]decane
• CAS NO: 19620-35-0
• Molecular Formula: C₁₁H₁₈O₂
• Molecular Weight: 182.26
• Product Categories: Miscellaneous
• Mol File: 19620-35-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 256.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.01±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 8-Isopropylidene-1,4-dioxa-spiro[4.5]decane(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Isopropylidene-1,4-dioxa-spiro[4.5]decane(19620-35-0)
• EPA Substance Registry System: 8-Isopropylidene-1,4-dioxa-spiro[4.5]decane(19620-35-0)

Safety Data

• Hazardous Substances Data: 19620-35-0(Hazardous Substances Data)

Upstream product

• 15681-48-8 lithium dimethylcuprate 
• 175020-73-2 4-(dibromomethylene)cyclohexanone ethylene ketal 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 24470-78-8 isopropyltriphenylphosphonium iodide 
• 1530-33-2 isopropyltriphenylphosphonium bromide 
• 917481-50-6 1-(isopropylsulfonyl)-3,5-bis(trifluoromethyl)benzene 

Downstream Products

• 19620-36-1 4-(propan-2-ylidene)cyclohexan-1-one 
• 5432-85-9 4-isopropyl-cyclohexanone 
• 163514-11-2 4-isopropyl-2-(pent-4-ynyl)cyclohexanone 
• 866606-96-4 (5S)-5-isopropyl-2-oxo-1-(pent-4-ynyl)cyclohexanecarboxylic acid methyl ester 
• 34131-94-7 4-isopropylidene-2-methylcyclohexanone 
• 334775-25-6 [4-Isopropylidene-2-methyl-cyclohex-(E)-ylidene]-((R)-1-phenyl-ethyl)-amine 
• 51941-39-0 1,7-dibromo-p-menth-4⁽⁸⁾-ene 
• 6876-10-4 menthadiene-1⁽⁷⁾,4⁽⁸⁾ 
• 50429-75-9 (r-1,c-4)-1,4,7,8-tetrabromo-p-menthane 
• 175020-74-3 4-isopropylidene-cyclohexanol 
• 175020-77-6 4-isopropylidenecyclohexyl mesylate 

Relevant articles and documents

Domino Aryne Annulation via a Nucleophilic-Ene Process

1,2-Benzdiyne equivalents possess the unique property that they can react with two arynophiles through iteratively generated 1,2- and 2,3-aryne intermediates. Upon rational modification on the second leaving group of these aryne precursors, a domino aryne annulation approach was developed through a nucleophilic-ene reaction sequence. Various benzo-fused N-heterocyclic frameworks were achievable under transition metal-free conditions with a broad substrate scope.

A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl–Alkyl Cross-Coupling Reactions

Coupling of readily available boronic acids and diazo compounds has emerged recently as a powerful metal-free carbon–carbon bond forming method. However, the difficulty in forming the unstable diazo compound partner in a mild fashion has hitherto limited their general use and the scope of the transformation. Here, we report the application of oxadiazolines as precursors for the generation of an unstable family of diazo compounds using flow UV photolysis and their first use in divergent protodeboronative and oxidative C(sp2)?C(sp3) cross-coupling processes, with excellent functional-group tolerance.

N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

A compound represented by the formula: (I) wherein R1 represents a methoxy group, a hydroxyl group or a hydrogen atom; R2 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkylcarbonyl group or an arylcarbonyl group; and D represents a group represented by the formula (A), (B) or (C) below. (A) (B) (C) This compound is useful as a therapeutic agent for a pain or inflammation induced by any one of various morbid conditions such as neuropathic pain, rheumatoid arthritis and osteoarthritis.