196395-00-3Relevant articles and documents
Thiol inhibitors of endothelin-converting enzyme
Deprez, Pierre,Guillaume, Jacques,Dumas, Jacques,Vevert, Jean-Paul
, p. 2317 - 2322 (1996)
Synthesis and structure activity relationships of a series of thiol inhibitors of the endothelin-converting enzyme (ECE) are presented. Optimisation of the stereochemistry as well as of the P'1 and P'2 residues led to inhibitors with similar potency to that of phosphoramidon.