19672-01-6

Basic information

• Product Name: 2-ethyl-3,5-dimethoxyphenol
• Synonyms: 2-ethyl-3,5-dimethoxyphenol
• CAS NO: 19672-01-6
• Molecular Weight: 182.219
• Mol File: 19672-01-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-ethyl-3,5-dimethoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-3,5-dimethoxyphenol(19672-01-6)
• EPA Substance Registry System: 2-ethyl-3,5-dimethoxyphenol(19672-01-6)

Safety Data

• Hazardous Substances Data: 19672-01-6(Hazardous Substances Data)

Upstream product

• 106800-22-0 2-(2,4,6-trimethoxyphenyl)ethyl bromide 
• 832-87-1 2-(2,4,6-trimethoxyphenyl)ethan-1-ol 
• 621-23-8 1,2,3-trimethoxybenzene 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 108-73-6 3,5-dihydroxyphenol 
• 1026183-20-9 2-(1-hydroxyethyl)-3,5-dimethoxyphenol 
• 67827-55-8 1-ethyl-2,4,6-trimethoxybenzene 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 
• 708-76-9 2-hydroxy-4,6-dimethoxybenzaldehyde 

Downstream Products

• 144688-19-7 1-(3-ethyl-2-hydroxy-4,6-dimethoxyphenyl)but-2-en-1-one 
• 531502-69-9 8-ethyl-5,7-dimethoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one 

Relevant articles and documents

3-site piperazinylchalcone derivative, and pharmaceutical composition and applications thereof

The present invention relates to a 3-site piperazinylchalcone derivative, which has a structure formula represented by a general formula (I) defined in the specification, wherein R is one selected from a substituted or unsubstituted phenyl group, a fused ring group and substituted or a unsubstituted heterocyclic group. The present invention further provides a pharmaceutical composition of the3-site piperazinylchalcone derivative, and applications thereof. According to the present invention, the results of the activity test based on P-gp target show that the 3-site piperazinylchalcone derivative and the pharmaceutical composition have good activity, can provide practical value in the treatment of the multidrug resistance of tumors, can solve the technical problems of difficult synthesis and high cost in the synthesis of the reversing agent used in the prior art, and is meaningful.

Deoxygenation of α,β-unsaturated acylphenols through ethyl o-acylphenylcarbonates with Luche reduction

An efficient protocol for deoxygenation of α,β-unsaturated acylphenols through ethyl o-acylphenylcarbonates with Luche reduction is described. The reaction shows very good selectivity and tolerates a wide range of functionalities on α,β-unsaturated acylphenols, giving corresponding 2-allylphenols in good to excellent yields.

Synthesis of novel flavonoid derivatives as potential HIV-integrase inhibitors

Eighteen novel flavonoid derivatives - substituted chalcones and flavones were synthesized and characterized by using NMR, IR, UV/Vis spectroscopy and elemental analysis. The target compounds were achieved by using a sequence of simple and effective reactions starting from phloroglucinol. The initial hydroxyl groups were protected by methylation and in the final flavones the 5-OH group was selectively demethylated by means of AlBr3. 5-methoxy flavones exhibit a strong fluorescence, which was quenched after the removal of the methyl group.