19677-37-3Relevant articles and documents
Production process of 2-methyl-2-(4-chlorphenyl)-1, 3-propylene glycol
-
Paragraph 0023-0026, (2020/07/12)
The invention discloses a production process of 2-methyl-2-(4-chlorphenyl)-1, 3-propylene glycol. The process comprises the following steps: taking p-chloroiodobenzene and diethyl malonate as initialraw materials; firstly, subjecting the p-chloroiodobenzene and diethyl malonate to coupling reaction to prepare a compound 3; carrying out alkylation reaction on the compound 3 and methyl iodide to obtain a compound 4; reacting the compound 4 with lithium aluminum hydride to obtain a 2-methyl-2-(4-chlorphenyl)-1, 3-propylene glycol crude product; and finally, subjecting the 2-methyl-2-(4-chlorphenyl)-1, 3-propylene glycol to a recrystallization procedure, thus obtaining the target product 2-methyl-2-(4-chlorphenyl)-1, 3-propylene glycol.
Oxidative Coupling of Aryl Boron Reagents with sp3-Carbon Nucleophiles: the Enolate Chan-Evans-Lam Reaction
Moon, Patrick J.,Halperlin, Heather M.,Lundgren, Rylan J.
supporting information, p. 1894 - 1898 (2016/08/31)
Reported is a versatile new oxidative method for the arylation of activated methylene species. Under mild reaction conditions (RT to 40 C), Cu(OTf)2 mediates the selective coupling of functionalized aryl boron species with a variety of stabilized sp3-nucl
3-aryl-6-methoxy-2-oxo-1,2-dihydroquinoline-4-carbonitriles as solvent and pH independent green fluorescent dyes
Enoua, Guy Crepin,Uray, Georg,Stadlbauer, Wolfgang
, p. 1415 - 1421 (2013/02/22)
Highly fluorescent and stable 3-aryl-6-methoxy-2-oxoquinoline-4- carbonitriles 6 (λexc = 408 nm and λem = 510 nm) were synthesized starting from appropriate arylmalonates 2. Ring closure reaction with p-anisidine gave 4-hydroxyquinol