199437-08-6

Basic information

• Product Name: 2-(4-Chloro-phenyl)-2-(2-cyano-ethyl)-malonic acid diethyl ester
• Synonyms: 2-(4-Chloro-phenyl)-2-(2-cyano-ethyl)-malonic acid diethyl ester
• CAS NO: 199437-08-6
• Molecular Weight: 323.776
• Mol File: 199437-08-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-Chloro-phenyl)-2-(2-cyano-ethyl)-malonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chloro-phenyl)-2-(2-cyano-ethyl)-malonic acid diethyl ester(199437-08-6)
• EPA Substance Registry System: 2-(4-Chloro-phenyl)-2-(2-cyano-ethyl)-malonic acid diethyl ester(199437-08-6)

Safety Data

• Hazardous Substances Data: 199437-08-6(Hazardous Substances Data)

Upstream product

• 19677-37-3 diethyl 2-(p-chlorophenyl)malonate 
• 109-75-1 but-3-enenitrile 

Relevant articles and documents

Potential GABAB Receptor Antagonists. X* the Synthesis of Further Analogues of Baclofen, Phaclbfen and Saclofen

In an attempt to obtain new compounds with binding activity at the GABAB receptor site, we report the synthesis of 3-amino-2-arylpropanoic acids, and the sulfonic, phosphonic and hydroxamic acid analogues. In addition, we report the synthesis of the isomer of phaclofen, 3-amino-1-(4-chlorophenyl)-propylphosphonic acid, and the higher homologue of baclofen, 5-amino-2-(4-chlorophenyl)pentanoic acid.