197523-46-9Relevant articles and documents
The synthesis of 8,8-disubstituted tricyclic analogs of artemisinin
Haraldson, Chad A.,Karle, Jean M.,Freeman, Sandy G.,Duvadie, Rohit K.,Avery, Mitchell A.
, p. 2357 - 2362 (2007/10/03)
Two tricyclic analogs of artemisinin were designed based on a Comparative Molecular Field Analysis (CoMFA) model, and synthesized for antimalarial testing as part of a program to construct and validate modeling tools for drug design of novel antimlarial agents based on the natural product lead, (+)-artemisinin.