197802-88-3

Basic information

• Product Name: 6-chloro-2-methyl-N⁴-(2,4,6-trimethyl-phenyl)-pyrimidine-4,5-diamine
• CAS NO: 197802-88-3
• Molecular Weight: 276.769
• Mol File: 197802-88-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-methyl-N⁴-(2,4,6-trimethyl-phenyl)-pyrimidine-4,5-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-methyl-N⁴-(2,4,6-trimethyl-phenyl)-pyrimidine-4,5-diamine(197802-88-3)
• EPA Substance Registry System: 6-chloro-2-methyl-N⁴-(2,4,6-trimethyl-phenyl)-pyrimidine-4,5-diamine(197802-88-3)

Safety Data

• Hazardous Substances Data: 197802-88-3(Hazardous Substances Data)

Upstream product

• 197802-86-1 2-methyl-5-nitro-6-(2,4,6-trimethyl-phenylamino)-3H-pyrimidin-4-one 
• 53925-27-2 2-methyl-4,6-dihydroxy-5-nitropyrimidine 
• 82779-50-8 4,6-dichloro-2-methyl-5-nitropyrimidine 
• 1194-22-5 2-methyl-4,6-dihydroxypyrimidine 
• 175140-70-2 4-N-(2,4,6-trimethylphenyl)-6-chloro-2-methyl-5-nitropyrimidin-4-amine 

Relevant articles and documents

Purin-8-ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists

A series of purin-8-ones was prepared and discovered to have excellent binding affinity to the CRH-R1 receptor. Structure-activity studies focused on amine side-chain optimization, urea substitution and pyridyl isostere incorporation. Thus, the highly potent purin-8-ones show promise as a new class of potential anxiolytics and/or antidepressants.