198065-80-4

Basic information

• Product Name: Benzoic acid, 4-[[(1-iminopentyl)amino]methyl]-, methyl ester
• CAS NO: 198065-80-4
• Molecular Formula: C14H20N2O2
• Molecular Weight: 248.325
• Mol File: 198065-80-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[[(1-iminopentyl)amino]methyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[[(1-iminopentyl)amino]methyl]-, methyl ester(198065-80-4)
• EPA Substance Registry System: Benzoic acid, 4-[[(1-iminopentyl)amino]methyl]-, methyl ester(198065-80-4)

Safety Data

• Hazardous Substances Data: 198065-80-4(Hazardous Substances Data)

Upstream product

• 57246-71-6 methyl pentanimidate 
• 18469-52-8 methyl 4-(aminomethyl)benzoate 

Downstream Products

• 133040-03-6 2-n-butyl-1-[(4-carbomethoxyphenyl)methyl]-1H-imidazol-5-carboxaldehyde 
• 159708-89-1 methyl 4-[(2-butyl-4-formyl-1H-imidazol-1-yl)methyl]benzoate 

Relevant articles and documents

A New Regioselective Synthesis of 1,2,5-Trisubstituted 1H-Imidazoles and Its Application to the Development of Eprosartan

A new method is presented for the preparation of 1,2-disubstitued-1H-imidazole-5-carboxaldehydes by the reaction of N-monosubstituted amidines with 2-halo-3-alkoxy-2-propenals. The reaction is highly regioselective with ratios of 1,2,5:1,2,4-imidazolecarboxaldehydes ranging from 85:15 to 100: 0. This methodology could be extended with similar results to the synthesis of imidazole-5-nitriles by the reaction of 2-bromo-3-methoxy-2-propenenitrile with N-monosubstituted amidines.