199522-60-6

Basic information

• Product Name: 1-[3-(1-triphenylmethylimidazol-4-yl)propyl]-3-[3-[N-(4-bromobenzyl)-N-(pyridin-2-yl)amino]propyl]thiourea
• Synonyms: 1-[3-(1-triphenylmethylimidazol-4-yl)propyl]-3-[3-[N-(4-bromobenzyl)-N-(pyridin-2-yl)amino]propyl]thiourea
• CAS NO: 199522-60-6
• Molecular Weight: 729.787
• Mol File: 199522-60-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-[3-(1-triphenylmethylimidazol-4-yl)propyl]-3-[3-[N-(4-bromobenzyl)-N-(pyridin-2-yl)amino]propyl]thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(1-triphenylmethylimidazol-4-yl)propyl]-3-[3-[N-(4-bromobenzyl)-N-(pyridin-2-yl)amino]propyl]thiourea(199522-60-6)
• EPA Substance Registry System: 1-[3-(1-triphenylmethylimidazol-4-yl)propyl]-3-[3-[N-(4-bromobenzyl)-N-(pyridin-2-yl)amino]propyl]thiourea(199522-60-6)

Safety Data

• Hazardous Substances Data: 199522-60-6(Hazardous Substances Data)

Upstream product

• 195053-88-4 2-[3-(1-trityl-1H-imidazol-4-yl)propyl]isoindoline-1,3-dione 
• 199522-62-8 3-propyl isothiocyanate 
• 195053-89-5 4-(3-aminopropyl)-1-(triphenylmethyl)-imidazole 
• 199522-61-7 N₁-(4-bromobenzyl)-N₁-(pyridin-2-yl)-propane-1,3-diamine 
• 152030-49-4 3-(1-trityl-1H-imidazol-4-yl)propan-1-ol 
• 31434-93-2 methyl 3-(4-imidazolyl)propionate 
• 102676-60-8 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester 
• 76-83-5 trityl chloride 
• 38585-73-8 N-(2-pyridinyl)-1,3-propandiamine 
• 109-04-6 2-bromo-pyridine 

Relevant articles and documents

USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE

The invention relates to the use of a somatostatin receptor ligand of nonpeptide origin, e.g. of general formula (Ia) or (Ib) or a pharmaceutically acceptable salt thereof, which has high and/or selective affinity to the somatostatin receptor protein designated SSTR4, for the preparation of a medicament for the treatment of a disease associated with an adverse condition in the retina and/or iris-ciliary body of a mammal. Such conditions being high intraocular pressure (IOP) and/or deep ocular infections. The diseases which may be treated are e.g. glaucoma, stromal keratitis, iritis, retinitis, cataract and conjunctivitis.

Use of somatostatin agonists and antagonists for treating diseases related to the eye

The invention relates to the use of a somatostatin receptor ligand of nonpeptide origin, e.g. of the general formula Ia or Ib or a pharmaceutically acceptable salt thereof, which has high and/or selective affinity to the somatostatin receptor protein designated SSTR4 and, for the preparation of a medicament for the treatment of a disease associated with an adverse condition in the retina and/or iris-ciliary body of a mammal. Such conditions are high intraocular pressure (IOP) and/or deep ocular infections. The diseases which may be treated are e.g. glaucoma, stromal keratitis, iritis, retinitis, cataract and conjunctivitis.