19999-87-2 Usage
Description
Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is a high-purity organometallic compound featuring a nickel(II) center coordinated by two tricyclohexylphosphine ligands. Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is known for its catalytic properties and is widely utilized in various chemical reactions, making it a valuable asset in the field of organic chemistry.
Uses
Used in Catalyst Industry:
Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is used as a catalyst for a variety of chemical reactions, enhancing the efficiency and selectivity of the processes.
1. Dehydrobrominative Polycondensation:
In this application, Bis(tricyclohexylphosphine)nickel(II) chloride, 99% acts as a catalyst to facilitate the dehydrobrominative polycondensation of various monomers, leading to the formation of polymers with improved properties.
2. Arylation Reactions:
Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is used as a catalyst in arylation reactions, promoting the formation of carbon-carbon bonds between an aryl halide and an organometallic reagent, which is crucial for the synthesis of various organic compounds.
3. Cross-Coupling:
Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is employed as a catalyst in cross-coupling reactions, enabling the formation of carbon-carbon bonds between different organic molecules, which is essential for the synthesis of complex organic structures.
4. Suzuki-Miyaura Cross-Coupling Reactions:
In the field of palladium-catalyzed cross-coupling reactions, Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is used as a catalyst to facilitate the Suzuki-Miyaura cross-coupling of aryl halides with organoboron compounds, leading to the formation of biaryl compounds.
5. Kumada Coupling of Diaryl Sulfates with Grignard Reagents:
Bis(tricyclohexylphosphine)nickel(II) chloride, 99% serves as a catalyst in the Kumada coupling of diaryl sulfates with Grignard reagents, promoting the formation of carbon-carbon bonds and contributing to the synthesis of various organic molecules.
6. Olefin Dimerization:
Bis(tricyclohexylphosphine)nickel(II) chloride, 99% is used as a catalyst in olefin dimerization reactions, where it promotes the formation of larger olefins from smaller olefin molecules, which is important for the production of various chemicals and materials.
Reaction
An approach to five-membered lactams from aliphatic amides and terminal acetylenes by nickel catalysis.
Synthesis of biaryls through nickel-catalyzed Suzuki-Miyaura coupling of amides by carbon-nitrogen bond cleavage.
Ni-catalyzed borylation of aryl fluorides via C-F cleavage.
Nickeland palladium–catalyzed coupling of aryl fluorosulfonates with aryl boronic acids enabled by sulfuryl fluoride.
Nickel-catalyzed one-pot synthesis of biaryls from phenols and arylboronic acids via C-O activation using TCT reagents.
Check Digit Verification of cas no
The CAS Registry Mumber 19999-87-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,9 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19999-87:
(7*1)+(6*9)+(5*9)+(4*9)+(3*9)+(2*8)+(1*7)=192
192 % 10 = 2
So 19999-87-2 is a valid CAS Registry Number.
InChI:InChI=1/2C18H33P.2ClH.Ni/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;;;/h2*16-18H,1-15H2;2*1H;/q;;;;+2/p-2
19999-87-2Relevant articles and documents
Catalyst and application thereof in synthesis of aromatic fluorine compounds
-
Paragraph 0027-0029, (2020/11/10)
The invention belongs to the field of catalyst preparation and application, and particularly relates to a catalyst and application thereof in synthesis of aromatic fluorine compounds. The nickel catalyst is dichloro-bis-(tri-cyclohexylphosphine) nickel, and the molecular formula of the nickel catalyst is Ni (Py3) 2Cl2. The nickel catalyst is applied to catalyzing inorganic fluoride to replace aromatic chloride to synthesize fluoride. The catalyst has the advantages of easily available reagents, simple catalyst synthesis, simple operation conditions, low reaction temperature, high reaction yield and less time consumption.
A broadly applicable strategy for entry into homogeneous nickel(0) catalysts from air-stable nickel(II) complexes
Standley, Eric A.,Smith, Stacey J.,Mueller, Peter,Jamison, Timothy F.
supporting information, p. 2012 - 2018 (2014/05/20)
A series of air-stable nickel complexes of the form L2Ni(aryl) X (L = monodentate phosphine, X = Cl, Br) and LNi(aryl)X (L = bis-phosphine) have been synthesized and are presented as a library of precatalysts suitable for a wide variety of nickel-catalyzed transformations. These complexes are easily synthesized from low-cost NiCl2·6H2O or NiBr 2·3H2O and the desired ligand followed by addition of 1 equiv of Grignard reagent. A selection of these complexes were characterized by single-crystal X-ray diffraction, and an analysis of their structural features is provided. A case study of their use as precatalysts for the nickel-catalyzed carbonyl-ene reaction is presented, showing superior reactivity in comparison to reactions using Ni(cod)2. Furthermore, as the precatalysts are all stable to air, no glovebox or inert-atmosphere techniques are required to make use of these complexes for nickel-catalyzed reactions.
