200418-21-9 Usage
Abbreviation
AFBI
Chemical Composition
Derivative of indole
Functional Groups
Benzoyl group
Bromine atom
Dimethylamide moiety
Biological/Pharmaceutical Potential
Anti-cancer Properties:
Studied for potential as an anti-cancer agent
Ability to inhibit the growth of certain cancer cell lines
Inhibition of Protein Kinase C:
Potential inhibitor of protein kinase C
Protein kinase C plays a role in numerous cellular processes
Ongoing Research
Continued investigation into potential uses and effects
Aim of developing new and effective pharmaceutical products
Check Digit Verification of cas no
The CAS Registry Mumber 200418-21-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,0,4,1 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 200418-21:
(8*2)+(7*0)+(6*0)+(5*4)+(4*1)+(3*8)+(2*2)+(1*1)=69
69 % 10 = 9
So 200418-21-9 is a valid CAS Registry Number.
200418-21-9Relevant articles and documents
Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists
Curtin, Michael L.,Davidsen, Steven K.,Heyman, H. Robin,Garland, Robert B.,Sheppard, George S.,Florjancic, Alan S.,Xu, Lianhong,Carrera Jr., George M.,Steinman, Douglas H.,Trautmann, Jeff A.,Albert, Daniel H.,Magoc, Terrance J.,Tapang, Paul,Rhein, David A.,Conway, Richard G.,Luo, Gongjin,Denissen, Jon F.,Marsh, Kennan C.,Morgan, Douglas W.,Summers, James B.
, p. 74 - 95 (2007/10/03)
Studies conducted with the goal of discovering a second-generation platelet-activating factor (PAF) antagonist have identified a novel class of potent and orally active antagonists which have high aqueous solubility and long duration of action in animal m