201002-41-7Relevant articles and documents
An efficient synthesis of D-ribo-C18-phytosphingosine and L-arabino-C18-phytosphingosine from D-fructose
Perali, Ramu Sridhar,Mandava, Suresh,Chalapala, Sudharani
, p. 9283 - 9290 (2011)
D-ribo-C18-phytosphingosine and L-arabino-C18- phytosphingosine were synthesised starting from commercially inexpensive D-fructose. Metal-mediated fragmentation and stereoselective reduction were used as key steps to provide the hydrophilic portion of D-ribo and L-arabino phytosphingosines. Grubbs' cross-metathesis and hydrogenation allowed the incorporation of hydrophobic tail.