201870-92-0

Basic information

• Product Name: (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-4-trifluoromethylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester
• CAS NO: 201870-92-0
• Molecular Weight: 577.665
• Mol File: 201870-92-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-4-trifluoromethylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-4-trifluoromethylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester(201870-92-0)
• EPA Substance Registry System: (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-4-trifluoromethylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester(201870-92-0)

Safety Data

• Hazardous Substances Data: 201870-92-0(Hazardous Substances Data)

Upstream product

• 764-52-3 (S)-2-amino-4-(trifluoromethylthio)butanoic 
• 24424-99-5 di-tert-butyl dicarbonate 
• 38155-18-9 L-leucyl-L-phenylalanine methyl ester 
• 201870-90-8 N-Boc-S-trifluoromethyl-L-homocysteine 

Downstream Products

• 143673-81-8 For-homoCys(S-CF₃)-Leu-Phe-OH 
• 201870-94-2 (S)-2-[(S)-2-((S)-2-Formylamino-4-trifluoromethylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

Synthesis of and chemotactic responses elicited by fMet-Leu-Phe analogs containing difluoro- and trifluoromethionine

N-Formylmethionylleucylphenylalanine tripeptides containing either L-difluoro- or L-trifluoromethionine as replacements for methionine were synthesized by solution methods. The fluorinated peptides were found to have potent chemoattractant activities on human neutrophils. Ab initio calculations were utilized to further understand the changes in electronic properties of the methionine side chain upon fluorination.